Hydrochlorothiazide Interactions
There are 472 drugs known to interact with hydrochlorothiazide, along with 11 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 15 are major, 424 are moderate, and 33 are minor.
- View all 472 medications that may interact with hydrochlorothiazide
- View hydrochlorothiazide alcohol/food interactions (2)
- View hydrochlorothiazide disease interactions (11)
Most frequently checked interactions
View interaction reports for hydrochlorothiazide and the medicines listed below.
- Aspir 81 (aspirin)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- Celebrex (celecoxib)
- CoQ10 (ubiquinone)
- Crestor (rosuvastatin)
- Cymbalta (duloxetine)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- Lexapro (escitalopram)
- Lipitor (atorvastatin)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- Nexium (esomeprazole)
- Norco (acetaminophen / hydrocodone)
- Norvasc (amlodipine)
- Ozempic (semaglutide)
- Plavix (clopidogrel)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Hydrochlorothiazide alcohol/food interactions
There are 2 alcohol/food interactions with hydrochlorothiazide.
Hydrochlorothiazide disease interactions
There are 11 disease interactions with hydrochlorothiazide which include:
- anuria
- electrolyte losses
- liver disease
- lupus erythematosus
- renal function disorders
- asthma
- diabetes
- hyperlipidemia
- hyperparathyroidism
- hyperuricemia
- thyroid function tests
Report options
More about hydrochlorothiazide
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- Reviews (185)
- Drug images
- Side effects
- Dosage information
- Patient tips
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- Support group
- Drug class: thiazide diuretics
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
