Estradiol topical Interactions
There are 258 drugs known to interact with estradiol topical, along with 17 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 33 are major, 209 are moderate, and 16 are minor.
- View all 258 medications that may interact with estradiol topical
- View estradiol topical alcohol/food interactions (2)
- View estradiol topical disease interactions (17)
Most frequently checked interactions
View interaction reports for estradiol topical and the medicines listed below.
- Allegra (fexofenadine)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- Claritin (loratadine)
- CoQ10 (ubiquinone)
- Cymbalta (duloxetine)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- Lexapro (escitalopram)
- Linzess (linaclotide)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Mucinex (guaifenesin)
- Myrbetriq (mirabegron)
- Ozempic (semaglutide)
- Probiotic Formula (bifidobacterium infantis / lactobacillus acidophilus)
- Restasis (cyclosporine ophthalmic)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zyrtec (cetirizine)
Estradiol topical alcohol/food interactions
There are 2 alcohol/food interactions with estradiol topical.
Estradiol topical disease interactions
There are 17 disease interactions with estradiol topical which include:
- abnormal vaginal bleeding
- carcinomas (estrogenic)
- hypercalcemia in breast cancer
- hypertension
- thromboembolism/cardiovascular
- hepatic neoplasms
- angioedema
- gallbladder disease
- hypercalcemia
- hyperlipidemia
- liver disease
- melasma
- depression
- fluid retention
- glucose intolerance
- retinal thrombosis
- thyroid function tests
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More about estradiol topical
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- Reviews (489)
- Side effects
- Dosage information
- During pregnancy
- Drug class: estrogens
- Breastfeeding
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
