Ortho-Prefest Interactions
There are 447 drugs known to interact with Ortho-Prefest (estradiol / norgestimate), along with 21 disease interactions, and 8 alcohol/food interactions. Of the total drug interactions, 72 are major, 349 are moderate, and 26 are minor.
- View Ortho-Prefest alcohol/food interactions (8)
- View Ortho-Prefest disease interactions (21)
Medications known to interact with Ortho-Prefest
Note: Showing generic names only.
A
- abametapir topical
- abrocitinib
- acarbose
- acetohexamide
- adagrasib
- adalimumab
- albiglutide
- alefacept
- alogliptin
- alosetron
- amikacin
- amikacin liposome
- aminoglutethimide
- aminophylline
- amitriptyline
- amobarbital
- amoxapine
- amoxicillin
- ampicillin
- amprenavir
- anagrelide
- anakinra
- anastrozole
- anisindione
- apalutamide
- aprepitant
- armodafinil
- asciminib
- ascorbic acid
- asenapine
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- atazanavir
- atorvastatin
- avacopan
- azithromycin
- aztreonam
B
- bacampicillin
- bacitracin
- baricitinib
- belzutifan
- bendamustine
- berotralstat
- betamethasone
- bexagliflozin
- bexarotene
- bimekizumab
- boceprevir
- bosentan
- brigatinib
- brivaracetam
- brodalumab
- budesonide
- bupropion
- butabarbital
- butalbital
C
- C1 esterase inhibitor (human)
- calaspargase pegol
- calcipotriene topical
- calcitriol topical
- canagliflozin
- canakinumab
- carbamazepine
- carbenicillin
- carfilzomib
- cefaclor
- cefadroxil
- cefamandole
- cefazolin
- cefditoren
- cefepime
- cefiderocol
- cefixime
- cefmetazole
- cefonicid
- cefoperazone
- cefotaxime
- cefotetan
- cefoxitin
- cefpodoxime
- cefprozil
- ceftaroline
- ceftazidime
- ceftibuten
- ceftizoxime
- ceftobiprole medocaril
- ceftriaxone
- cefuroxime
- cenobamate
- cephalexin
- cephalothin
- cephapirin
- cephradine
- chenodiol
- chloramphenicol
- chlorpropamide
- cholestyramine
- cimetidine
- cinoxacin
- ciprofloxacin
- cladribine
- clarithromycin
- clindamycin
- clobazam
- clomipramine
- clotrimazole
- cloxacillin
- clozapine
- cobicistat
- colesevelam
- colestipol
- colistimethate
- conestat alfa
- conivaptan
- corticorelin
- corticotropin
- cortisone
- cosyntropin
- cyclosporine
D
- dabrafenib
- dalbavancin
- dantrolene
- dapagliflozin
- daptomycin
- daridorexant
- darunavir
- dasatinib
- deferasirox
- deflazacort
- dehydroepiandrosterone
- delafloxacin
- delavirdine
- demeclocycline
- desipramine
- dexamethasone
- dicloxacillin
- dicumarol
- diltiazem
- dirithromycin
- divalproex sodium
- doripenem
- doxepin
- doxycycline
- dronedarone
- dulaglutide
- duloxetine
- duvelisib
E
- echinacea
- efavirenz
- elafibranor
- elagolix
- emapalumab
- empagliflozin
- enasidenib
- encorafenib
- enoxacin
- entrectinib
- enzalutamide
- eravacycline
- ertapenem
- ertugliflozin
- erythromycin
- eslicarbazepine
- ethanol
- etravirine
- exemestane
- exenatide
F
- fedratinib
- felbamate
- fenfluramine
- fentanyl
- fexinidazole
- fezolinetant
- fitusiran
- flibanserin
- fluconazole
- fludrocortisone
- fluvoxamine
- fosamprenavir
- fosaprepitant
- fosphenytoin
- fostamatinib
- frovatriptan
- furazolidone
G
- gatifloxacin
- gemifloxacin
- gentamicin
- glimepiride
- glipizide
- glyburide
- glycerol phenylbutyrate
- golimumab
- grepafloxacin
- griseofulvin
- guselkumab
H
I
- imatinib
- imipramine
- indinavir
- infliximab
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- iptacopan
- isavuconazonium
- isoniazid
- itraconazole
- ivacaftor
- ivosidenib
K
L
- lamotrigine
- lapatinib
- larotrectinib
- lefamulin
- lenacapavir
- lenalidomide
- lesinurad
- letermovir
- letrozole
- levobupivacaine
- levofloxacin
- levoketoconazole
- levothyroxine
- levothyroxine / liothyronine
- lidocaine
- linagliptin
- lincomycin
- linezolid
- liothyronine
- liotrix
- liraglutide
- lixisenatide
- lomefloxacin
- lomitapide
- lonafarnib
- lonapegsomatropin
- loracarbef
- lorlatinib
M
- mavacamten
- melatonin
- mephobarbital
- meropenem
- metformin
- methicillin
- methylprednisolone
- metreleptin
- metronidazole
- metyrapone
- mezlocillin
- mibefradil
- miconazole
- mifepristone
- miglitol
- miltefosine
- minocycline
- mitapivat
- mitotane
- mobocertinib
- modafinil
- momelotinib
- morphine
- morphine liposomal
- moxifloxacin
- mycophenolate mofetil
- mycophenolic acid
N
- nafcillin
- nalidixic acid
- naratriptan
- nateglinide
- nefazodone
- nelfinavir
- nemolizumab
- neomycin
- neratinib
- netilmicin
- nevirapine
- nicotine
- nilotinib
- nitrofurantoin
- norfloxacin
- nortriptyline
- novobiocin
O
- odevixibat
- ofloxacin
- olaparib
- olutasidenib
- omadacycline
- omaveloxolone
- oritavancin
- osilodrostat
- ospemifene
- oxacillin
- oxcarbazepine
- oxtriphylline
- oxytetracycline
P
- pacritinib
- paromomycin
- pegaspargase
- penicillin g benzathine
- penicillin g potassium
- penicillin g sodium
- penicillin v potassium
- pentobarbital
- perampanel
- pexidartinib
- phenobarbital
- phenylbutazone
- phenytoin
- pioglitazone
- piperacillin
- pirfenidone
- pirtobrutinib
- pitolisant
- pivmecillinam
- plazomicin
- polymyxin b
- pomalidomide
- posaconazole
- pralsetinib
- pramlintide
- prednisolone
- prednisone
- pretomanid
- primidone
- procaine penicillin
- protriptyline
R
- raloxifene
- ramelteon
- rasagiline
- repaglinide
- repotrectinib
- rifabutin
- rifampin
- rifapentine
- rilonacept
- ritlecitinib
- ritonavir
- roflumilast
- ropinirole
- rosiglitazone
- rosuvastatin
- rucaparib
- rufinamide
- ruxolitinib
- ruxolitinib topical
S
- saquinavir
- sarecycline
- sarilumab
- satralizumab
- saw palmetto
- saxagliptin
- secobarbital
- secukinumab
- selegiline
- selpercatinib
- selumetinib
- semaglutide
- siltuximab
- sirolimus
- sitagliptin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotagliflozin
- sotorasib
- sparfloxacin
- st. john's wort
- stiripentol
- streptomycin
- succinylcholine
- sugammadex
- sulfadiazine
- sulfadoxine
- sulfamethizole
- sulfamethoxazole
- sulfasalazine
- sulfinpyrazone
- sulfisoxazole
- suzetrigine
T
- tacrolimus
- tasimelteon
- tazemetostat
- tecovirimat
- tedizolid
- telaprevir
- telithromycin
- telotristat
- temsirolimus
- teriflunomide
- testolactone
- tetracycline
- thalidomide
- theophylline
- thyroid desiccated
- ticarcillin
- tigecycline
- tinidazole
- tipranavir
- tirzepatide
- tivozanib
- tizanidine
- tobramycin
- tocilizumab
- tofacitinib
- tolazamide
- tolbutamide
- topiramate
- tovorafenib
- tranexamic acid
- triamcinolone
- triamcinolone ophthalmic
- trimipramine
- trofinetide
- troglitazone
- troleandomycin
- trovafloxacin
- tucatinib
U
V
- vadadustat
- valproic acid
- vamorolone
- vancomycin
- varenicline
- vemurafenib
- vorasidenib
- voriconazole
- voxelotor
W
Z
Ortho-Prefest alcohol/food interactions
There are 8 alcohol/food interactions with Ortho-Prefest (estradiol / norgestimate).
Ortho-Prefest disease interactions
There are 21 disease interactions with Ortho-Prefest (estradiol / norgestimate) which include:
- abnormal vaginal bleeding
- carcinomas (estrogenic)
- hypercalcemia in breast cancer
- hypertension
- thromboembolism/cardiovascular
- hepatic neoplasms
- liver disease
- thromboembolism
- angioedema
- gallbladder disease
- hypercalcemia
- hyperlipidemia
- liver disease
- melasma
- depression
- fluid retention
- glucose intolerance
- retinal thrombosis
- thyroid function tests
- hyperlipidemia
- weight gain
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More about Ortho-Prefest (estradiol / norgestimate)
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: sex hormone combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.