Climara Drug Interactions
Currently displaying a list of 390 drugs known to interact with Climara (estradiol).
- 34 major drug interactions
- 336 moderate drug interactions
- 20 minor drug interactions
Medications known to interact with Climara
Note: Showing generic names only.
A
- abametapir topical
- abrocitinib
- acarbose
- acetohexamide
- adagrasib
- albiglutide
- alogliptin
- alosetron
- amikacin
- amikacin liposome
- aminoglutethimide
- aminophylline
- amitriptyline
- amobarbital
- amoxapine
- amoxicillin
- ampicillin
- anagrelide
- anastrozole
- anisindione
- apalutamide
- aprepitant
- armodafinil
- asciminib
- ascorbic acid
- asenapine
- atorvastatin
- avacopan
- azithromycin
- aztreonam
B
- bacampicillin
- bacitracin
- baricitinib
- belzutifan
- bendamustine
- berotralstat
- betamethasone
- bexagliflozin
- bexarotene
- boceprevir
- bosentan
- brigatinib
- budesonide
- bupropion
- butabarbital
- butalbital
C
- C1 esterase inhibitor (human)
- calcipotriene topical
- calcitriol topical
- canagliflozin
- carbamazepine
- carbenicillin
- carfilzomib
- cefaclor
- cefadroxil
- cefamandole
- cefazolin
- cefditoren
- cefepime
- cefiderocol
- cefixime
- cefmetazole
- cefonicid
- cefoperazone
- cefotaxime
- cefotetan
- cefoxitin
- cefpodoxime
- cefprozil
- ceftaroline
- ceftazidime
- ceftibuten
- ceftizoxime
- ceftobiprole medocaril
- ceftriaxone
- cefuroxime
- cenobamate
- cephalexin
- cephalothin
- cephapirin
- cephradine
- chenodiol
- chloramphenicol
- chlorpropamide
- cholestyramine
- cimetidine
- cinoxacin
- ciprofloxacin
- clarithromycin
- clindamycin
- clomipramine
- clotrimazole
- cloxacillin
- colestipol
- colistimethate
- conestat alfa
- conivaptan
- corticorelin
- corticotropin
- cortisone
- cosyntropin
- cyclosporine
D
- dabrafenib
- dalbavancin
- dantrolene
- dapagliflozin
- daptomycin
- daridorexant
- darunavir
- dasatinib
- deferasirox
- deflazacort
- dehydroepiandrosterone
- delafloxacin
- delavirdine
- demeclocycline
- desipramine
- dexamethasone
- dicloxacillin
- dicumarol
- diltiazem
- dirithromycin
- divalproex sodium
- doripenem
- doxepin
- doxycycline
- dronedarone
- dulaglutide
- duloxetine
- duvelisib
E
- echinacea
- efavirenz
- elafibranor
- elagolix
- empagliflozin
- encorafenib
- enoxacin
- enzalutamide
- eravacycline
- ertapenem
- ertugliflozin
- erythromycin
- eslicarbazepine
- etravirine
- exemestane
- exenatide
F
- fedratinib
- felbamate
- fenfluramine
- fentanyl
- fexinidazole
- fezolinetant
- fitusiran
- fluconazole
- fludrocortisone
- fluvoxamine
- fosaprepitant
- fosphenytoin
- fostamatinib
- furazolidone
G
- gatifloxacin
- gemifloxacin
- gentamicin
- glimepiride
- glipizide
- glyburide
- glycerol phenylbutyrate
- grepafloxacin
- griseofulvin
H
I
- imatinib
- imipramine
- indinavir
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- iptacopan
- isavuconazonium
- isoniazid
- itraconazole
- ivacaftor
- ivosidenib
K
L
- lamotrigine
- lapatinib
- larotrectinib
- lefamulin
- lenacapavir
- lenalidomide
- letermovir
- letrozole
- levobupivacaine
- levofloxacin
- levoketoconazole
- levothyroxine
- levothyroxine / liothyronine
- lidocaine
- linagliptin
- lincomycin
- linezolid
- liothyronine
- liotrix
- liraglutide
- lixisenatide
- lomefloxacin
- lonafarnib
- lonapegsomatropin
- loracarbef
- lorlatinib
M
- mavacamten
- melatonin
- mephobarbital
- meropenem
- metformin
- methicillin
- methylprednisolone
- metreleptin
- metronidazole
- metyrapone
- mezlocillin
- mibefradil
- miconazole
- mifepristone
- miglitol
- minocycline
- mitapivat
- mitotane
- mobocertinib
- modafinil
- momelotinib
- moxifloxacin
N
- nafcillin
- nalidixic acid
- nateglinide
- nefazodone
- nelfinavir
- neomycin
- netilmicin
- nevirapine
- nicotine
- nilotinib
- nitrofurantoin
- norfloxacin
- nortriptyline
- novobiocin
O
- ofloxacin
- olutasidenib
- omadacycline
- oritavancin
- osilodrostat
- ospemifene
- oxacillin
- oxcarbazepine
- oxtriphylline
- oxytetracycline
P
- pacritinib
- paromomycin
- penicillin g benzathine
- penicillin g potassium
- penicillin g sodium
- penicillin v potassium
- pentobarbital
- pexidartinib
- phenobarbital
- phenylbutazone
- phenytoin
- pioglitazone
- piperacillin
- pirfenidone
- pirtobrutinib
- pitolisant
- pivmecillinam
- plazomicin
- polymyxin b
- pomalidomide
- posaconazole
- pralsetinib
- pramlintide
- prednisolone
- prednisone
- pretomanid
- primidone
- procaine penicillin
- protriptyline
R
- raloxifene
- ramelteon
- rasagiline
- repaglinide
- repotrectinib
- rifabutin
- rifampin
- rifapentine
- ritlecitinib
- ritonavir
- roflumilast
- ropinirole
- rosiglitazone
- rucaparib
- rufinamide
- ruxolitinib
- ruxolitinib topical
S
- saquinavir
- sarecycline
- saw palmetto
- saxagliptin
- secobarbital
- selpercatinib
- semaglutide
- sirolimus
- sitagliptin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotagliflozin
- sotorasib
- sparfloxacin
- st. john's wort
- stiripentol
- streptomycin
- succinylcholine
- sulfadiazine
- sulfadoxine
- sulfamethizole
- sulfamethoxazole
- sulfasalazine
- sulfinpyrazone
- sulfisoxazole
- suzetrigine
T
- tacrolimus
- tasimelteon
- tazemetostat
- tecovirimat
- tedizolid
- telaprevir
- telithromycin
- telotristat
- temsirolimus
- testolactone
- tetracycline
- thalidomide
- theophylline
- thyroid desiccated
- ticarcillin
- tigecycline
- tinidazole
- tipranavir
- tirzepatide
- tizanidine
- tobramycin
- tofacitinib
- tolazamide
- tolbutamide
- tovorafenib
- tranexamic acid
- triamcinolone
- triamcinolone ophthalmic
- trimipramine
- trofinetide
- troglitazone
- troleandomycin
- trovafloxacin
- tucatinib
U
V
- vadadustat
- valproic acid
- vamorolone
- vancomycin
- varenicline
- vemurafenib
- vorasidenib
- voriconazole
- voxelotor
W
Z
Climara alcohol/food interactions
There are 4 alcohol/food interactions with Climara (estradiol).
Climara disease interactions
There are 17 disease interactions with Climara (estradiol) which include:
- abnormal vaginal bleeding
- carcinomas (estrogenic)
- hypercalcemia in breast cancer
- hypertension
- thromboembolism/cardiovascular
- hepatic neoplasms
- angioedema
- gallbladder disease
- hypercalcemia
- hyperlipidemia
- liver disease
- melasma
- depression
- fluid retention
- glucose intolerance
- retinal thrombosis
- thyroid function tests
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More about Climara (estradiol)
- Climara consumer information
- Check interactions
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- Reviews (62)
- Side effects
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- During pregnancy
- Generic availability
- Drug class: estrogens
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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