Help I Can't Sleep Interactions
There are 448 drugs known to interact with Help I Can't Sleep (diphenhydramine), along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 15 are major, 430 are moderate, and 3 are minor.
- View all 448 medications that may interact with Help I Can't Sleep
- View Help I Can't Sleep alcohol/food interactions (1)
- View Help I Can't Sleep disease interactions (8)
Most frequently checked interactions
View interaction reports for Help I Can't Sleep (diphenhydramine) and the medicines listed below.
Help I Can't Sleep alcohol/food interactions
There is 1 alcohol/food interaction with Help I Can't Sleep (diphenhydramine).
Help I Can't Sleep disease interactions
There are 8 disease interactions with Help I Can't Sleep (diphenhydramine) which include:
- depression
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
Report options
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More about Help I Can't Sleep (diphenhydramine)
- Compare alternatives
- Drug images
- Latest FDA alerts (2)
- Side effects
- Dosage information
- During pregnancy
- Drug class: anticholinergic antiemetics
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
