DPH Interactions
There are 449 drugs known to interact with DPH (diphenhydramine), along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 15 are major, 431 are moderate, and 3 are minor.
- View all 449 medications that may interact with DPH
- View DPH alcohol/food interactions (1)
- View DPH disease interactions (8)
Most frequently checked interactions
View interaction reports for DPH (diphenhydramine) and the medicines listed below.
- acetaminophen
- Acticon (dexbrompheniramine / pseudoephedrine)
- Advil Cold and Sinus (ibuprofen / pseudoephedrine)
- Aerius (desloratadine)
- Alcohol (contained in alcoholic beverages) (ethanol)
- allantoin / lidocaine / petrolatum topical
- Allegra-D 24 Hour (fexofenadine / pseudoephedrine)
- Ambien (zolpidem)
- amlodipine
- amoxicillin
- Arimidex (anastrozole)
- aspirin
- atenolol
- Ativan (lorazepam)
- atorvastatin
- azithromycin
- cannabis
- escitalopram
- eszopiclone
- fluoxetine
- hydroxyzine
- levocetirizine
- lisdexamfetamine
- losartan
- melatonin
- multivitamin
- omeprazole
- Prozac (fluoxetine)
- risperidone
- Ventolin (albuterol)
DPH alcohol/food interactions
There is 1 alcohol/food interaction with DPH (diphenhydramine).
DPH disease interactions
There are 8 disease interactions with DPH (diphenhydramine) which include:
- depression
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
Report options
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More about DPH (diphenhydramine)
- Compare alternatives
- Latest FDA alerts (2)
- Side effects
- Dosage information
- During pregnancy
- Drug class: anticholinergic antiemetics
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.