Diphenmax Interactions
There are 449 drugs known to interact with Diphenmax (diphenhydramine), along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 15 are major, 431 are moderate, and 3 are minor.
- View all 449 medications that may interact with Diphenmax
- View Diphenmax alcohol/food interactions (1)
- View Diphenmax disease interactions (8)
Most frequently checked interactions
View interaction reports for Diphenmax (diphenhydramine) and the medicines listed below.
- albuterol
- Aquaphor (emollients topical)
- aspirin
- baclofen
- budesonide
- carisoprodol
- cetirizine
- clonazepam
- Ear Wax Remover (carbamide peroxide otic)
- enalapril
- Estradiol G GAM (estradiol)
- Fentanyl Transdermal System (fentanyl)
- fluticasone
- gabapentin
- Generlac (lactulose)
- Guaifenesin DAC (codeine / guaifenesin / pseudoephedrine)
- guanfacine
- hydromorphone
- ibuprofen
- Iron Sulfate (ferrous sulfate)
- Lortab (acetaminophen / hydrocodone)
- medroxyprogesterone
- Milk of Magnesia (magnesium hydroxide)
- MiraLAX (polyethylene glycol 3350)
- Motrin (ibuprofen)
- Nexium (esomeprazole)
- Nitro-Bid (nitroglycerin)
- omeprazole
- Procycle Multi Vitamin with Minerals (multivitamin with minerals)
- Promethazine VC (phenylephrine / promethazine)
Diphenmax alcohol/food interactions
There is 1 alcohol/food interaction with Diphenmax (diphenhydramine).
Diphenmax disease interactions
There are 8 disease interactions with Diphenmax (diphenhydramine) which include:
- depression
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
Report options
More about Diphenmax (diphenhydramine)
- Compare alternatives
- Latest FDA alerts (2)
- Side effects
- Dosage information
- During pregnancy
- Drug class: anticholinergic antiemetics
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.