Diphendryl Interactions
There are 448 drugs known to interact with Diphendryl (diphenhydramine), along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 14 are major, 432 are moderate, and 2 are minor.
- View all 448 medications that may interact with Diphendryl
- View Diphendryl alcohol/food interactions (1)
- View Diphendryl disease interactions (8)
Most frequently checked interactions
View interaction reports for Diphendryl (diphenhydramine) and the medicines listed below.
- acetaminophen
- albuterol
- albuterol / ipratropium
- amlodipine
- amoxicillin
- Aspir 81 (aspirin)
- aspirin
- Aspirin Low Strength (aspirin)
- baclofen
- bupropion
- clonidine
- docusate
- Flexeril (cyclobenzaprine)
- furosemide
- gabapentin
- levothyroxine
- lisinopril
- lorazepam
- meclizine
- melatonin
- omeprazole
- oxycodone
- pantoprazole
- sertraline
- Singulair (montelukast)
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
Diphendryl alcohol/food interactions
There is 1 alcohol/food interaction with Diphendryl (diphenhydramine).
Diphendryl disease interactions
There are 8 disease interactions with Diphendryl (diphenhydramine) which include:
- depression
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
More about Diphendryl (diphenhydramine)
- Compare alternatives
- Latest FDA alerts (2)
- Side effects
- Dosage information
- During pregnancy
- Drug class: anticholinergic antiemetics
- Breastfeeding
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.