Dextromethorphan/diphenhydramine/phenylephrine Interactions
There are 651 drugs known to interact with dextromethorphan/diphenhydramine/phenylephrine, along with 12 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 98 are major, 549 are moderate, and 4 are minor.
- View all 651 medications that may interact with dextromethorphan/diphenhydramine/phenylephrine
- View dextromethorphan/diphenhydramine/phenylephrine alcohol/food interactions (1)
- View dextromethorphan/diphenhydramine/phenylephrine disease interactions (12)
Most frequently checked interactions
View interaction reports for dextromethorphan / diphenhydramine / phenylephrine and the medicines listed below.
- Advair HFA (fluticasone / salmeterol)
- Advil (ibuprofen)
- Alcohol (contained in alcoholic beverages) (ethanol)
- Augmentin (amoxicillin / clavulanate)
- Benadryl (diphenhydramine)
- Benzedrex (propylhexedrine nasal)
- Botox (onabotulinumtoxinA)
- Bromfed DM (brompheniramine / dextromethorphan / pseudoephedrine)
- BroveX PEB DM (brompheniramine / dextromethorphan / phenylephrine)
- Children's Zyrtec (cetirizine)
- Childrens Ibuprofen Berry (ibuprofen)
- Claritin (loratadine)
- Coenzyme Q10 (ubiquinone)
- Concerta (methylphenidate)
- Cymbalta (duloxetine)
- Depakote Sprinkles (divalproex sodium)
- Dextromethorphan HBr Adult Formula (dextromethorphan)
- Fasenra (benralizumab)
- Glucophage (metformin)
- Imitrex (sumatriptan)
- Imodium (loperamide)
- Infant's Tylenol (acetaminophen)
- Klonopin (clonazepam)
- MegaKrill (omega-3 polyunsaturated fatty acids)
- Methotrexate LPF Sodium (methotrexate)
- Metoprolol Succinate ER (metoprolol)
- ProAir HFA (albuterol)
- Prozac (fluoxetine)
- Tylenol (acetaminophen)
- Zyrtec (cetirizine)
Dextromethorphan/diphenhydramine/phenylephrine alcohol/food interactions
There is 1 alcohol/food interaction with dextromethorphan / diphenhydramine / phenylephrine.
Dextromethorphan/diphenhydramine/phenylephrine disease interactions
There are 12 disease interactions with dextromethorphan / diphenhydramine / phenylephrine which include:
- depression
- cardiovascular disease
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- BPH
- diabetes
- glaucoma
Report options
More about dextromethorphan / diphenhydramine / phenylephrine
- dextromethorphan/diphenhydramine/phenylephrine consumer information
- Compare alternatives
- Side effects
- Dosage information
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.