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Dextromethorphan / Diphenhydramine / Phenylephrine Dosage

Medically reviewed on November 27, 2017.

Applies to the following strengths: varying strength; 75 mg-25 mg-7.5 mg/5 mL; 15 mg-12.5 mg-15 mg/5 mL

Usual Adult Dose for Allergic Rhinitis

Dextromethorphan/diphenhydrAMINE/PE 15 mg-12.5 mg-15 mg/5 mL oral suspension, extended release: 5 to 10 mL orally every 12 hours.

Dextromethorphan/diphenhydrAMINE/PE 75 mg-25 mg-7.5 mg/5 mL oral suspension, extended release: 5 to 10 mL orally every 12 hours.

Usual Adult Dose for Cold Symptoms

Dextromethorphan/diphenhydrAMINE/PE 15 mg-12.5 mg-15 mg/5 mL oral suspension, extended release: 5 to 10 mL orally every 12 hours.

Dextromethorphan/diphenhydrAMINE/PE 75 mg-25 mg-7.5 mg/5 mL oral suspension, extended release: 5 to 10 mL orally every 12 hours.

Usual Adult Dose for Cough and Nasal Congestion

Dextromethorphan/diphenhydrAMINE/PE 15 mg-12.5 mg-15 mg/5 mL oral suspension, extended release: 5 to 10 mL orally every 12 hours.

Dextromethorphan/diphenhydrAMINE/PE 75 mg-25 mg-7.5 mg/5 mL oral suspension, extended release: 5 to 10 mL orally every 12 hours.

Usual Adult Dose for Sinusitis

Dextromethorphan/diphenhydrAMINE/PE 15 mg-12.5 mg-15 mg/5 mL oral suspension, extended release: 5 to 10 mL orally every 12 hours.

Dextromethorphan/diphenhydrAMINE/PE 75 mg-25 mg-7.5 mg/5 mL oral suspension, extended release: 5 to 10 mL orally every 12 hours.

Usual Pediatric Dose for Allergic Rhinitis

Dextromethorphan/diphenhydrAMINE/PE 15 mg-12.5 mg-15 mg/5 mL oral suspension, extended release:
2 to 5 years: 2.5 mL orally every 12 hours.
6 to 11 years: 5 mL orally every 12 hours.
12 years or older: 5 to 10 mL orally every 12 hours.

Dextromethorphan/diphenhydrAMINE/PE 75 mg-25 mg-7.5 mg/5 mL oral suspension, extended release
2 to 5 years: 1.25 to 2.5 mL orally every 12 hours.
6 to 11 years: 2.5 to 5 mL orally every 12 hours.
12 years or older: 5 to 10 mL orally every 12 hours.

Usual Pediatric Dose for Cold Symptoms

Dextromethorphan/diphenhydrAMINE/PE 15 mg-12.5 mg-15 mg/5 mL oral suspension, extended release:
2 to 5 years: 2.5 mL orally every 12 hours.
6 to 11 years: 5 mL orally every 12 hours.
12 years or older: 5 to 10 mL orally every 12 hours.

Dextromethorphan/diphenhydrAMINE/PE 75 mg-25 mg-7.5 mg/5 mL oral suspension, extended release
2 to 5 years: 1.25 to 2.5 mL orally every 12 hours.
6 to 11 years: 2.5 to 5 mL orally every 12 hours.
12 years or older: 5 to 10 mL orally every 12 hours.

Usual Pediatric Dose for Cough and Nasal Congestion

Dextromethorphan/diphenhydrAMINE/PE 15 mg-12.5 mg-15 mg/5 mL oral suspension, extended release:
2 to 5 years: 2.5 mL orally every 12 hours.
6 to 11 years: 5 mL orally every 12 hours.
12 years or older: 5 to 10 mL orally every 12 hours.

Dextromethorphan/diphenhydrAMINE/PE 75 mg-25 mg-7.5 mg/5 mL oral suspension, extended release
2 to 5 years: 1.25 to 2.5 mL orally every 12 hours.
6 to 11 years: 2.5 to 5 mL orally every 12 hours.
12 years or older: 5 to 10 mL orally every 12 hours.

Usual Pediatric Dose for Sinusitis

Dextromethorphan/diphenhydrAMINE/PE 15 mg-12.5 mg-15 mg/5 mL oral suspension, extended release:
2 to 5 years: 2.5 mL orally every 12 hours.
6 to 11 years: 5 mL orally every 12 hours.
12 years or older: 5 to 10 mL orally every 12 hours.

Dextromethorphan/diphenhydrAMINE/PE 75 mg-25 mg-7.5 mg/5 mL oral suspension, extended release
2 to 5 years: 1.25 to 2.5 mL orally every 12 hours.
6 to 11 years: 2.5 to 5 mL orally every 12 hours.
12 years or older: 5 to 10 mL orally every 12 hours.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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