Codeine/phenylephrine Interactions
There are 648 drugs known to interact with codeine/phenylephrine, along with 20 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 143 are major, 503 are moderate, and 2 are minor.
- View all 648 medications that may interact with codeine/phenylephrine
- View codeine/phenylephrine alcohol/food interactions (2)
- View codeine/phenylephrine disease interactions (20)
Most frequently checked interactions
View interaction reports for codeine / phenylephrine and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- Advair Diskus (fluticasone / salmeterol)
- Advil (ibuprofen)
- Afrin NoDrip Extra Moisturizing (oxymetazoline nasal)
- Alcohol (contained in alcoholic beverages) (ethanol)
- Aleve (naproxen)
- Allegra Allergy (fexofenadine)
- Amoclan (amoxicillin / clavulanate)
- Azithromycin Dose Pack (azithromycin)
- Bactrim (sulfamethoxazole / trimethoprim)
- Benadryl (diphenhydramine)
- Benadryl Allergy (diphenhydramine)
- Botox (onabotulinumtoxinA)
- Calcium 600 D (calcium / vitamin d)
- Celebrex (celecoxib)
- Centrum Silver Women's (multivitamin with minerals)
- Claritin 24 Hour Allergy (loratadine)
- Colace (docusate)
- Compazine (prochlorperazine)
- Cosentyx (secukinumab)
- Cymbalta (duloxetine)
- Diphen (diphenhydramine)
- Diurex Aquagels (pamabrom)
- Dulcolax Laxative (bisacodyl)
- Effexor XR (venlafaxine)
- Elavil (amitriptyline)
- Elmiron (pentosan polysulfate sodium)
- Emgality (galcanezumab)
- Enbrel (etanercept)
Codeine/phenylephrine alcohol/food interactions
There are 2 alcohol/food interactions with codeine / phenylephrine.
Codeine/phenylephrine disease interactions
There are 20 disease interactions with codeine / phenylephrine which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- BPH
- diabetes
- glaucoma
More about codeine / phenylephrine
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
See also:
Benadryl
Benadryl is an antihistamine and is used to treat sneezing, runny nose, itching and other ...
Promethazine DM
Promethazine DM is used for allergic rhinitis, cold symptoms, cough
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Banophen
Banophen is used for allergic reactions, allergic rhinitis, cold symptoms, cough, extrapyramidal ...
Benadryl Allergy
Benadryl Allergy is used for allergic reactions, allergic rhinitis, allergies, cold symptoms ...
Pseudoephedrine/triprolidine
Pseudoephedrine/triprolidine is used for allergic rhinitis, cold symptoms
Echinacea
Echinacea is used for cold symptoms, condylomata acuminata, herbal supplementation
Chlorpheniramine
Chlorpheniramine is used for allergic reactions, allergic rhinitis, allergies, cold symptoms, food ...
Diphenhydramine
Diphenhydramine is an antihistamine used to treat sneezing, runny nose, itching, hives and other ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.