Codeine / phenylephrine Drug Interactions
A total of 1039 drugs are known to interact with codeine / phenylephrine.
- 343 major drug interactions
- 692 moderate drug interactions
- 4 minor drug interactions
Check for interactions with codeine / phenylephrine
Common medications checked in combination with codeine / phenylephrine
- Advair Diskus (fluticasone / salmeterol)
- Advil (ibuprofen)
- Aleve (naproxen)
- Azithromycin Dose Pack (azithromycin)
- Cymbalta (duloxetine)
- Excedrin Migraine (acetaminophen / aspirin / caffeine)
- Flonase (fluticasone nasal)
- Imodium (loperamide)
- Imodium A-D (loperamide)
- Lidoderm (lidocaine topical)
- Mobic (meloxicam)
- Paxil (paroxetine)
- Percocet (acetaminophen / oxycodone)
- phenylephrine (Sudafed PE Congestion, Neo-Synephrine, Phenyl-T, Nasal Decongestant PE, Vazculep, Suphedrine PE, Help I Have A Stuffy Nose, Despec-SF, Sudogest PE, Nasop12, Triaminic Thin Strips Cold with Stuffy Nose, Dimetapp Toddler's Drops Decongestant, Congest Aid II, AH-Chew D, Gilchew IR, Little Colds Decongestant, Lusonal, Contac-D, Nasop, Ricobid-D, PediaCare Children's Decongestant, Sudafed PE Children's Nasal Decongestant)
- ProAir HFA (albuterol)
- Prozac (fluoxetine)
- QNASL (beclomethasone nasal)
- Singulair (montelukast)
- Sudafed 12-Hour (pseudoephedrine)
- Vicodin (acetaminophen / hydrocodone)
- Xanax (alprazolam)
Codeine / phenylephrine alcohol/food interactions
There is 1 alcohol/food interaction with codeine / phenylephrine
Codeine / phenylephrine disease interactions
There are 20 disease interactions with codeine / phenylephrine which include:
- impaired GI motility
- infectious diarrhea
- liver disease
- prematurity
- renal dysfunction
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- cardiovascular disease
- adrenal insufficiency
- biliary spasm
- hypothyroidism
- seizure disorders
- urinary retention
- arrhythmias
- BPH
- diabetes
- glaucoma
More about codeine/phenylephrine
- Codeine/phenylephrine Side Effects
- During Pregnancy
- Dosage Information
- Drug class: upper respiratory combinations
- FDA Alerts (5)
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No information available. |
Do not stop taking any medications without consulting your healthcare provider.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
