Codeine / phenylephrine Side Effects
Respiratory depression has been associated with antitussive use of codeine in young children. Respiratory depression and death have occurred in children who received codeine in the postoperative period following tonsillectomy and/or adenoidectomy. Further investigation has shown these patients to be ultra-rapid metabolizers of codeine. Children with obstructive sleep apnea who are treated with codeine appear to be particularly sensitive to the respiratory depressant effects of codeine.[Ref]
Frequency not reported: Respiratory depression
Frequency not reported: Respiratory distress[Ref]
Frequency not reported: Ischemia[Ref]
Frequency not reported: Rash[Ref]
Frequency not reported: Euphoria, dysphoria, transient hallucination, disorientation
Frequency not reported: CNS depression, lightheadedness, dizziness, sedation, headache, convulsions, weakness
Frequency not reported: Restlessness, dizziness, tremor, weakness[Ref]
Frequency not reported: Visual disturbances[Ref]
Frequency not reported: Pain[Ref]
1. "Product Information. Ala-Hist AC (codeine-phenylephrine)." Poly Pharmaceuticals Inc, Quitman, MS.
2. "Product Information. Promethazine VC with Codeine (codeine / phenylephrine/promethazine)." Par Pharmaceutical Inc (formerly Qualitest Pharmaceuticals Inc), Huntsville, AL.
More about codeine / phenylephrine
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Some side effects may not be reported. You may report them to the FDA.