Codeine/guaifenesin/pseudoephedrine Interactions
There are 647 drugs known to interact with codeine/guaifenesin/pseudoephedrine, along with 22 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 133 are major, 509 are moderate, and 5 are minor.
- View all 647 medications that may interact with codeine/guaifenesin/pseudoephedrine
- View codeine/guaifenesin/pseudoephedrine alcohol/food interactions (2)
- View codeine/guaifenesin/pseudoephedrine disease interactions (22)
Most frequently checked interactions
View interaction reports for codeine / guaifenesin / pseudoephedrine and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- Advair Diskus (fluticasone / salmeterol)
- Ambien (zolpidem)
- Aspercreme (trolamine salicylate topical)
- Avelox (moxifloxacin)
- Benadryl (diphenhydramine)
- Bromaphen (brompheniramine)
- Centrum Silver Women's (multivitamin with minerals)
- Cepacol Dual Relief Sore Throat + Cough Spray (benzocaine / dextromethorphan)
- Claritin (loratadine)
- Colace (docusate)
- Concerta (methylphenidate)
- Copaxone (glatiramer)
- Coricidin HBP Cough & Cold (chlorpheniramine / dextromethorphan)
- Enbrel (etanercept)
- Endocet (acetaminophen / oxycodone)
- Ery-Tab (erythromycin)
- Estroven (multivitamin with minerals)
- Fentanyl Transdermal System (fentanyl)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Flovent (fluticasone)
- Fluad (influenza virus vaccine, inactivated)
- Fluzone High-Dose Quadrivalent (influenza virus vaccine, inactivated)
- Hydrocodone HD (chlorpheniramine / hydrocodone / phenylephrine)
- Hydromet (homatropine / hydrocodone)
- Ibuprofen PMR (ibuprofen)
- Ritalin-SR (methylphenidate)
- Vitamin D3 (cholecalciferol)
Codeine/guaifenesin/pseudoephedrine alcohol/food interactions
There are 2 alcohol/food interactions with codeine / guaifenesin / pseudoephedrine.
Codeine/guaifenesin/pseudoephedrine disease interactions
There are 22 disease interactions with codeine / guaifenesin / pseudoephedrine which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- GI narrowing
- PKU
- BPH
- diabetes
- glaucoma
Report options
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More about codeine / guaifenesin / pseudoephedrine
- codeine/guaifenesin/pseudoephedrine consumer information
- Compare alternatives
- Reviews (1)
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.