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Codeine / Guaifenesin / Pseudoephedrine Dosage

Applies to the following strength(s): 10 mg-100 mg-30 mg/5 mL ; 20 mg-200 mg-60 mg/5 mL ; 10 mg-100 mg-22.5 mg/5 mL ; 9 mg-200 mg-30 mg/5 mL ; 10 mg-400 mg-60 mg ; 20 mg-400 mg-60 mg ; 10 mg-400 mg-40 mg ; 20 mg-400 mg-40 mg ; 10 mg-400 mg-20 mg ; 20 mg-400 mg-20 mg ; 10 mg-400 mg-30 mg ; 20 mg-400 mg-30 mg ; 8 mg-200 mg-30 mg/5 mL

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Cold Symptoms

codeine/guaifenesin/PSE 10 mg-100 mg-22.5 mg/5 mL oral liquid:
10 mL orally every 6 to 8 hours. Do not exceed 40 mL in 24 hours.

codeine/guaifenesin/PSE 10 mg-100 mg-30 mg/5 mL oral liquid:
10 mL orally every 6 hours. Do not exceed 40 mL in 24 hours.

codeine/guaifenesin/PSE 10 mg-400 mg-20 mg oral tablet,
codeine/guaifenesin/PSE 10 mg-400 mg-30 mg oral tablet, or
codeine/guaifenesin/PSE 10 mg-400 mg-40 mg oral tablet, or
codeine/guaifenesin/PSE 20 mg-400 mg-20 mg oral tablet, or
codeine/guaifenesin/PSE 20 mg-400 mg-30 mg oral tablet, or
codeine/guaifenesin/PSE 20 mg-400 mg-40 mg oral tablet:
1 tablet orally every 4 to 6 hours, not to exceed 6 tablets in 24 hours.

codeine/guaifenesin/PSE 10 mg-400 mg-60 mg oral tablet, or
codeine/guaifenesin/PSE 20 mg-400 mg-60 mg oral tablet:
1 tablet orally every 4 to 6 hours, not to exceed 4 tablets in 24 hours.

codeine/guaifenesin/PSE 9 mg-200 mg-30 mg/5 mL oral liquid, or
codeine/guaifenesin/PSE 8 mg-200 mg-30 mg/5 mL oral liquid:
10 mL orally every 4 to 6 hours. Do not exceed 40 mL in 24 hours.

Usual Pediatric Dose for Cold Symptoms

codeine/guaifenesin/PSE 10 mg-100 mg-30 mg/5 mL oral liquid:
2 years to 5 years:
2.5 mL orally every 6 hours. Do not exceed 10 mL in 24 hours.
6 years to 12 years:
5 mL orally every 6 hours. Do not exceed 20 mL in 24 hours.
13 years or older:
10 mL orally every 6 hours. Do not exceed 40 mL in 24 hours.

codeine/guaifenesin/PSE 10 mg-100 mg-22.5 mg/5 mL oral liquid:
6 years to 11 years:
5 mL orally every 6 to 8 hours. Do not exceed 20 mL in 24 hours.
12 years or older:
10 mL orally every 6 hours. Do not exceed 40 mL in 24 hours.

codeine/guaifenesin/PSE 10 mg-400 mg-20 mg oral tablet,
codeine/guaifenesin/PSE 10 mg-400 mg-30 mg oral tablet,
codeine/guaifenesin/PSE 10 mg-400 mg-40 mg oral tablet,
codeine/guaifenesin/PSE 20 mg-400 mg-20 mg oral tablet,
codeine/guaifenesin/PSE 20 mg-400 mg-30 mg oral tablet, or
codeine/guaifenesin/PSE 20 mg-400 mg-40 mg oral tablet:
12 years or older:
1 tablet orally every 4 to 6 hours. Do not exceed 6 tablets in 24 hours.
6 years to 11 years:
1/2 tablet orally every 4 to 6 hours. Do not exceed 3 tablets in 24 hours.

codeine/guaifenesin/PSE 10 mg-400 mg-60 mg oral tablet, or
codeine/guaifenesin/PSE 20 mg-400 mg-60 mg oral tablet:
12 years or older:
1 tablet orally every 4 to 6 hours. Do not exceed 4 tablets in 24 hours.
6 years to 11 years:
1/2 tablet orally every 4 to 6 hours. Do not exceed 2 tablets in 24 hours.

codeine/guaifenesin/PSE 9 mg-200 mg-30 mg/5 mL oral liquid, or
codeine/guaifenesin/PSE 8 mg-200 mg-30 mg/5 mL oral liquid:
6 years to 11 years:
5 mL orally every 4 to 6 hours. Do not exceed 20 mL in 24 hours.
12 years or older:
10 mL orally every 4 to 6 hours. Do not exceed 40 mL in 24 hours.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

The FDA has not approved use of over-the-counter cough and cold medications to children aged less than 2 years, and proper dosing for children in this age group has not been studied. Clinicians should be aware of the risk for serious illness or fatal overdose from administration of cough and cold medications to children aged less than 2 years. Clinicians should be certain that caregivers understand 1) the importance of administering cough and cold medications only as directed and 2) the risk for overdose if they administer additional medications that might contain the same ingredient.

Dialysis

Data not available

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