Suboxone (buprenorphine / naloxone) Drug Interactions
A total of 1108 drugs are known to interact with Suboxone (buprenorphine / naloxone).
- 321 major drug interactions
- 776 moderate drug interactions
- 11 minor drug interactions
Check for interactions
Most frequently checked interactions
View interaction reports for Suboxone (buprenorphine / naloxone) and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- alprazolam (Xanax, Xanax XR, Alprazolam Intensol, Niravam)
- Ambien (zolpidem)
- clonazepam (Klonopin, Klonopin Wafer)
- clonidine (Catapres, Kapvay, Clonidine ER, Catapres-TTS, Nexiclon XR, Duraclon, Jenloga)
- Cymbalta (duloxetine)
- Flexeril (cyclobenzaprine)
- gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
- hydrocodone (Hysingla ER, Zohydro ER, Vantrela ER)
- ibuprofen (Advil, Motrin, IBU, Children's Motrin, Proprinal, Advil Liqui-Gels, Ibu-8, Motrin IB, Motrin Childrens, Rufen, Childrens Ibuprofen Berry, IBU-200, Ibuprofen PMR, Advil Migraine, Ibu-Tab, Genpril, Menadol, Advil Children's, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, Addaprin, Motrin Infant Drops, NeoProfen, Caldolor, Motrin Pediatric, Haltran, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Nuprin, Advil Junior Strength, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- Lexapro (escitalopram)
- lisinopril (Zestril, Prinivil, Qbrelis)
- Lyrica (pregabalin)
- methadone (Methadose, Methadone Diskets, Dolophine, Methadose Sugar-Free)
- naltrexone (Vivitrol, Revia, Depade)
- Neurontin (gabapentin)
- Norco (acetaminophen / hydrocodone)
- omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
- oxycodone (OxyContin, Roxicodone, Xtampza ER, OxyIR, Oxaydo, RoxyBond, Percolone, Oxecta, Oxydose, Oxyfast, M-Oxy, ETH-Oxydose, Endocodone, Roxicodone Intensol, Dazidox)
- Percocet (acetaminophen / oxycodone)
- Prozac (fluoxetine)
- Seroquel (quetiapine)
- Subutex (buprenorphine)
- tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, ConZip, Zydol, Tramal SR, GenRx Tramadol, Zamadol, Ryzolt, Tramedo, Larapam SR, Tramahexal SR, Tramahexal, Zydol XL, Rybix ODT, Ultram ODT)
- trazodone (Desyrel, Oleptro, Desyrel Dividose)
- Valium (diazepam)
- Vyvanse (lisdexamfetamine)
- Xanax (alprazolam)
- Zoloft (sertraline)
Suboxone (buprenorphine / naloxone) alcohol/food interactions
There is 1 alcohol/food interaction with Suboxone (buprenorphine / naloxone)
Suboxone (buprenorphine / naloxone) disease interactions
There are 18 disease interactions with Suboxone (buprenorphine / naloxone) which include:
- CV disorders
- impaired GI motility
- infectious diarrhea
- liver disease
- prematurity
- renal dysfunction
- acute MI
- drug dependence
- intracranial pressure
- respiratory depression
- liver disease
- renal
- septic shock
- adrenal insufficiency
- biliary spasm
- hypothyroidism
- seizure disorders
- urinary retention
More about Suboxone (buprenorphine / naloxone)
- Suboxone Side Effects
- During Pregnancy
- Dosage Information
- Patient Tips
- Drug Images
- Compare Alternatives
- Support Group
- Pricing & Coupons
- En Español
- 555 Reviews
- Generic Availability
- Drug class: narcotic analgesic combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
