Sudafed PE Cold & Cough Interactions
There are 624 drugs known to interact with Sudafed PE Cold & Cough (acetaminophen / dextromethorphan / guaifenesin / phenylephrine), along with 7 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 95 are major, 512 are moderate, and 17 are minor.
- View all 624 medications that may interact with Sudafed PE Cold & Cough
- View Sudafed PE Cold & Cough alcohol/food interactions (1)
- View Sudafed PE Cold & Cough disease interactions (7)
Most frequently checked interactions
View interaction reports for Sudafed PE Cold & Cough (acetaminophen / dextromethorphan / guaifenesin / phenylephrine) and the medicines listed below.
- acetaminophen
- albuterol
- Aleve (naproxen)
- aspirin
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- bupropion
- cephalexin
- Claritin (loratadine)
- clonazepam
- doxycycline
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- gabapentin
- hydrochlorothiazide
- ibuprofen
- loratadine
- metformin
- multivitamin
- naproxen
- omeprazole
- ondansetron
- pantoprazole
- prednisone
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
Sudafed PE Cold & Cough alcohol/food interactions
There is 1 alcohol/food interaction with Sudafed PE Cold & Cough (acetaminophen / dextromethorphan / guaifenesin / phenylephrine).
Sudafed PE Cold & Cough disease interactions
There are 7 disease interactions with Sudafed PE Cold & Cough (acetaminophen / dextromethorphan / guaifenesin / phenylephrine) which include:
Report options
More about Sudafed PE Cold & Cough (acetaminophen / dextromethorphan / guaifenesin / phenylephrine)
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.