Acetaminophen / Dextromethorphan / Guaifenesin / Phenylephrine Dosage

Medically reviewed on December 11, 2017.

Usual Adult Dose for Cold Symptoms

Acetaminophen/dextromethorphan/guaifenesin/PE 325 mg-10 mg-200 mg-5 mg oral tablet, or
Acetaminophen/dextromethorphan/guaifenesin/PE 325 mg-10 mg-100 mg-5 mg oral tablet:
2 tablets orally every 4 hours not to exceed 12 tablets daily.

Acetaminophen/dextromethorphan/guaifenesin/PE 500 mg-20 mg-400 mg-10 mg oral tablet:
1 tablet orally every 4 to 6 hours not to exceed 6 tablets daily.

Acetaminophen/dextromethorphan/guaifenesin/PE 325 mg-10 mg-200 mg-5 mg/15 mL oral liquid:
30 mL orally every 4 hours not to exceed 180 mL daily.

Acetaminophen/dextromethorphan/guaifenesin/PE 650 mg-20 mg-400 mg-10 mg/20 mL oral liquid:
20 mL orally every 4 hours not to exceed 6 doses (120 mL) daily

Usual Adult Dose for Influenza

Acetaminophen/dextromethorphan/guaifenesin/PE 325 mg-10 mg-200 mg-5 mg oral tablet, or
Acetaminophen/dextromethorphan/guaifenesin/PE 325 mg-10 mg-100 mg-5 mg oral tablet:
2 tablets orally every 4 hours not to exceed 12 tablets daily.

Acetaminophen/dextromethorphan/guaifenesin/PE 500 mg-20 mg-400 mg-10 mg oral tablet:
1 tablet orally every 4 to 6 hours not to exceed 6 tablets daily.

Acetaminophen/dextromethorphan/guaifenesin/PE 325 mg-10 mg-200 mg-5 mg/15 mL oral liquid:
30 mL orally every 4 hours not to exceed 180 mL daily.

Acetaminophen/dextromethorphan/guaifenesin/PE 650 mg-20 mg-400 mg-10 mg/20 mL oral liquid:
20 mL orally every 4 hours not to exceed 6 doses (120 mL) daily

Usual Pediatric Dose for Cold Symptoms

Acetaminophen/dextromethorphan/guaifenesin/PE 325 mg-10 mg-200 mg-5 mg oral tablet, or
Acetaminophen/dextromethorphan/guaifenesin/PE 325 mg-10 mg-100 mg-5 mg oral tablet:
12 years or older: 2 tablets orally every 4 hours not to exceed 12 tablets daily.

Acetaminophen/dextromethorphan/guaifenesin/PE 500 mg-20 mg-400 mg-10 mg oral tablet:
6 to 11 years: 1/2 tablet orally every 4 to 6 hours not to exceed 3 tablets daily.
12 years or older: 1 tablet orally every 4 to 6 hours not to exceed 6 tablets daily.

Acetaminophen/dextromethorphan/guaifenesin/PE 325 mg-10 mg-200 mg-5 mg/10 mL oral liquid:
6 to 11 years: 10 mL orally every 4 hours not to exceed 50 mL daily.
Acetaminophen/dextromethorphan/guaifenesin/PE 325 mg-10 mg-200 mg-5 mg/15 mL oral liquid:
12 years or older: 30 mL orally every 4 hours not to exceed 180 mL daily.

Acetaminophen/dextromethorphan/guaifenesin/PE 650 mg-20 mg-400 mg-10 mg/20 mL oral liquid:
12 years or older: 20 mL orally every 4 hours not to exceed 6 doses (120 mL) daily

Usual Pediatric Dose for Influenza

Acetaminophen/dextromethorphan/guaifenesin/PE 325 mg-10 mg-200 mg-5 mg oral tablet, or
Acetaminophen/dextromethorphan/guaifenesin/PE 325 mg-10 mg-100 mg-5 mg oral tablet:
12 years or older: 2 tablets orally every 4 hours not to exceed 12 tablets daily.

Acetaminophen/dextromethorphan/guaifenesin/PE 500 mg-20 mg-400 mg-10 mg oral tablet:
6 to 11 years: 1/2 tablet orally every 4 to 6 hours not to exceed 3 tablets daily.
12 years or older: 1 tablet orally every 4 to 6 hours not to exceed 6 tablets daily.

Acetaminophen/dextromethorphan/guaifenesin/PE 325 mg-10 mg-200 mg-5 mg/10 mL oral liquid:
6 to 11 years: 10 mL orally every 4 hours not to exceed 50 mL daily.
Acetaminophen/dextromethorphan/guaifenesin/PE 325 mg-10 mg-200 mg-5 mg/15 mL oral liquid:
12 years or older: 30 mL orally every 4 hours not to exceed 180 mL daily.

Acetaminophen/dextromethorphan/guaifenesin/PE 650 mg-20 mg-400 mg-10 mg/20 mL oral liquid:
12 years or older: 20 mL orally every 4 hours not to exceed 6 doses (120 mL) daily

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

Other Comments

Store the oral liquid at room temperature

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer