VEGF/VEGFR inhibitors
What are VEGF/VEGFR inhibitors?
Vascular endothelial growth factor (VEGF)/ vascular endothelial growth factor receptor (VEGFR) inhibitors are agents that inhibit the activity of VEGF and VEGFR. VEGR and VEGFR (a tyrosine kinase receptor) signaling modulates angiogenesis, which involves making of new blood vessels from existing blood vessels.
Abnormal angiogenesis is known to occur in cancer, degenerative eye conditions and other conditions that involve inflammation. Specific monoclonal antibodies can be used as VEGF inhibitors and particular tyrosine kinase inhibitors are used as VEGFR inhibitors.
Vascular endothelial growth factor (VEGF)/ vascular endothelial growth factor receptor (VEGFR) inhibitors are used to treat various types of cancers.
List of VEGF/VEGFR inhibitors
Drug Name | Avg. Rating | Reviews |
---|---|---|
Votrient (Pro) Generic name: pazopanib |
82 reviews | |
Sutent (Pro) Generic name: sunitinib |
30 reviews | |
Avastin (Pro) Generic name: bevacizumab |
30 reviews | |
Nexavar (Pro) Generic name: sorafenib |
14 reviews | |
Cabometyx (Pro) Generic name: cabozantinib |
12 reviews | |
Stivarga (Pro) Generic name: regorafenib |
10 reviews | |
Lenvima (Pro) Generic name: lenvatinib |
4 reviews | |
Iclusig (Pro) Generic name: ponatinib |
2 reviews | |
Cometriq (Pro) Generic name: cabozantinib |
2 reviews | |
Zaltrap (Pro) Generic name: ziv-aflibercept |
1 review | |
Inlyta (Pro) Generic name: axitinib |
1 review | |
Zirabev (Pro) Generic name: bevacizumab | No reviews | |
Vegzelma (Pro) Generic name: bevacizumab | No reviews | |
Mvasi (Pro) Generic name: bevacizumab | No reviews | |
Jobevne Generic name: bevacizumab | No reviews | |
Fruzaqla (Pro) Generic name: fruquintinib | No reviews | |
Fotivda (Pro) Generic name: tivozanib | No reviews | |
Cyramza (Pro) Generic name: ramucirumab | No reviews | |
Caprelsa (Pro) Generic name: vandetanib | No reviews | |
Avzivi (Pro) Generic name: bevacizumab | No reviews | |
Alymsys (Pro) Generic name: bevacizumab | No reviews | |
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective). |
See also
Medical conditions treated or associated with VEGF/VEGFR inhibitors:
- Acute Lymphoblastic Leukemia
- Cervical Cancer
- Chronic Myelogenous Leukemia
- Colorectal Cancer
- Endometrial Cancer
- Fallopian Tube Cancer
- Gastric Cancer
- Gastrointestinal Stromal Tumor
- Glioblastoma Multiforme
- Hepatic Tumor
- Hepatocellular Carcinoma
- Neuroendocrine Tumors
- Non Small Cell Lung Cancer
- Ovarian Cancer
- Pancreatic Cancer
- Peritoneal Cancer
- Renal Cell Carcinoma
- Soft Tissue Sarcoma
- Stomach Cancer
- Thyroid Cancer
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.