Voquezna Dosage

Generic name: vonoprazan fumarate 13.36mg
Dosage form: tablet
Drug class: Proton pump inhibitors

Medically reviewed by Drugs.com. Last updated on Jul 22, 2024.

Healing of Erosive Esophagitis

The recommended adult oral dosage is VOQUEZNA 20 mg once daily for 8 weeks for the treatment of healing of erosive esophagitis and relief of associated heartburn.

Maintenance of Healed Erosive Esophagitis

The recommended adult oral dosage is VOQUEZNA 10 mg once daily for up to 6 months for the maintenance of healed erosive esophagitis and relief of associated heartburn.

Relief of Heartburn Associated with Non-Erosive Gastroesophageal Reflux Disease

Treatment of H. pylori Infection

Triple Therapy: The recommended adult oral dosage is VOQUEZNA 20 mg plus amoxicillin 1,000 mg plus clarithromycin 500 mg, each given twice daily (in the morning and evening, 12 hours apart) for 14 days.
Dual Therapy: The recommended adult oral dose is VOQUEZNA 20 mg given twice daily (in the morning and evening) plus amoxicillin 1,000 mg three times daily (in the morning, mid-day, and evening) for 14 days.
Also refer to the amoxicillin and clarithromycin full prescribing information.

Healing of Erosive Esophagitis

The recommended dosage of VOQUEZNA in adult patients with renal impairment is described in Table 1 below.

Table 1: Recommended VOQUEZNA Dosage in Patients with Renal Impairment: Healing of Erosive Esophagitis
Estimated glomerular filtration rate (GFR)	Recommended Dosage
30 mL/minute or greater	20 mg once daily
Less than 30 mL/minute	10 mg once daily

Maintenance of Healed Erosive Esophagitis or Relief of Heartburn Associated with Non-Erosive Gastroesophageal Reflux Disease

The recommended dosage of VOQUEZNA in adult patients with renal impairment is the same as for adult patients with normal renal function.

Treatment of H. pylori Infection

The recommended dosage of VOQUEZNA in adult patients with renal impairment is described in Table 2 below.

Table 2: Recommended VOQUEZNA Dosage in Patients with Renal Impairment: Treatment of H. pylori Infection*
Estimated GFR	Recommended Dosage
* Also refer to the Dosage and Administration section of the amoxicillin and clarithromycin prescribing information for dosage recommendations in patients with renal impairment.
30 mL/minute or greater	20 mg twice daily
Less than 30 mL/minute	Use is not recommended

Healing of Erosive Esophagitis

The recommended dosage of VOQUEZNA in adult patients with hepatic impairment is described in Table 3 below.

Maintenance of Healed Erosive Esophagitis or Relief of Heartburn Associated with Non-Erosive Gastroesophageal Reflux Disease

The recommended dosage of VOQUEZNA in adult patients with hepatic impairment is the same as for patients with normal hepatic function.

Treatment of H. pylori Infection

The recommended dosage of VOQUEZNA in adult patients with hepatic impairment is described in Table 4 below.

Take VOQUEZNA with or without food.
Swallow VOQUEZNA tablets whole; do not chew or crush the tablet.
Missed doses:
- For the healing or maintenance of healed erosive esophagitis, or the relief of heartburn associated with non-erosive gastroesophageal reflux disease: If a dose is missed, administer VOQUEZNA as soon as possible within 12 hours after the missed dose. If more than 12 hours have passed, skip the missed dose and administer the next dose at the regularly scheduled time.
- For the treatment of H. pylori infection: If a dose is missed, administer VOQUEZNA as soon as possible within 4 hours after the missed dose. If more than 4 hours have passed, skip the missed dose and administer the next dose at the regularly scheduled time. Continue the normal dosing schedule until the treatment is completed.