Sinequan Dosage
Generic name: doxepin hydrochloride
Dosage form: Capsules and Oral Concentrate
Drug classes: Miscellaneous anxiolytics, sedatives and hypnotics, Tricyclic antidepressants
Medically reviewed by Drugs.com. Last updated on Nov 11, 2024.
Recommended Dosage
For most patients with illness of mild to moderate severity, a starting daily dose of 75 mg is recommended. Dosage may subsequently be increased or decreased at appropriate intervals and according to individual response. The usual optimum dose range is 75 mg/day to 150 mg/day.
In more severely ill patients higher doses may be required with subsequent gradual increase to 300 mg/day if necessary. Additional therapeutic effect is rarely to be obtained by exceeding a dose of 300 mg/day.
In patients with very mild symptomatology or emotional symptoms accompanying organic disease, lower doses may suffice. Some of these patients have been controlled on doses as low as 25–50 mg/day.
The total daily dosage of SINEQUAN may be given on a divided or once-a-day dosage schedule. If the once-a-day schedule is employed, the maximum recommended dose is 150 mg/day. This dose may be given at bedtime. The 150 mg capsule strength is intended for maintenance therapy only and is not recommended for initiation of treatment.
Anti-anxiety effect is apparent before the antidepressant effect. Optimal antidepressant effect may not be evident for two to three weeks.
Frequently asked questions
More about Sinequan (doxepin)
- Check interactions
- Compare alternatives
- Reviews (9)
- Drug images
- Side effects
- During pregnancy
- Drug class: miscellaneous anxiolytics, sedatives and hypnotics
- Breastfeeding
Patient resources
Other brands
Professional resources
Other brands
Related treatment guides
See also:
Vraylar
Vraylar is a once a day antipsychotic medication used to treat mental health or mood disorders ...
Xolair
Xolair injection (omalizumab) is used to help improve allergic asthma, nasal polyps, and chronic ...
Rexulti
Rexulti (brexpiprazole) is a prescription antipsychotic medication used in the treatment of major ...
Lexapro
Lexapro is used to treat anxiety and major depressive disorder. Learn about side effects ...
Lorazepam
Lorazepam is in a group of drugs called benzodiazepines and is used to treat anxiety disorders ...
Venlafaxine
Venlafaxine is used to treat major depressive disorder, anxiety, and panic disorder. Learn about ...
Buspirone
Buspirone is used to treat symptoms of anxiety, such as fear, tension, irritability and dizziness ...
Alprazolam
Alprazolam is used to treat anxiety disorders, panic disorders, and anxiety. Learn about side ...
Hydroxyzine
Hydroxyzine is an antihistamine used to treat itching, hives, and anxiety. It also acts as a ...
Escitalopram
Escitalopram is an SSRI antidepressant used to treat major depressive disorder in adults and teens ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.