Sinequan User Reviews & Ratings

• fay...
• November 20, 2015

For Anxiety "If you're not able to take or no longer able to take SSRIs, SNRIs, and Benzos, this is a drug to consider. I've taken it off and on for decades. It helps tremendously in maintaining normalcy and is excellent for someone deprived of sleep. Takes time, but once adjusted, it will become less of a problem. Although it will continue to help for a good night's sleep. It's best to take this medication later in the afternoon until you do adjust. God bless."

• fay...
• Taken for 10 years or more
• September 20, 2015

For Depression "It works tremendously well on insomnia and really does help in maintaining normalcy in everyday life. Sleeping a lot at first, which in my case was a good thing. It's not the best for uplifting depression and doesn't help in taking away anxiety or panic attacks. The side effects for me were being easily bothered & hostile/angry. Will pass if you continue taking as directed, but each time you stop and then start again, the experience starts over. But keep in mind, side effects vary and it's different for each of us. What works for one might not work for another. I've been taking Sinequan/Doxepin for over two decades."

• Par...
• August 29, 2019

For Major Depressive Disorder "It’s the best antidepressant for major depression. I recommend it highly. I have no side effects. I take 250 mg a day in divided doses - one in the morning, one in the afternoon, and three at night. It took me a year to find it, and I love it. Thank you."

• rho...
• October 5, 2009

For Insomnia "Sinequan (doxepin) works very well for insomnia, especially since it not only causes drowsiness, but also because it relieves anxiety. A lot of insomnia is caused by overthinking or not being able to stop thinking or fretting. This is a good medicine for that. The only thing is it has more side effects than some of the newer drugs."

• pke...
• Taken for 6 months to 1 year
• May 24, 2023

"My new psychiatrist chose this to replace multiple prescription drugs I was using at the time. 25 mg was the initial dose, and even after 10 days, there was little change for me, other than the major issue of making me snap at people and feel anger/rage, which were and are uncharacteristic for me. He upped the dose to 50 mg, and the major issue went away, and all the other things the prescription was supposed to do, it did! Depression, anxiety, trouble sleeping, restless legs - all gone! A concern later discovered by a team of doctors I had was that I was taking this and other prescriptions which prolong or extend QTc time for heartbeats, something which could cause sudden cardiac death if not monitored carefully by a cardiologist. My cardiologist calculated my QTc time to be right at the border of the high acceptable normal range, so the other doctors wanted me to have medications adjusted to lower the QTc time and its risk. I had to stop Sinequan while temporarily."

• mit...
• June 5, 2008

For Depression "Worked really well. I suffer from chronic insomnia as well and found it worked well on the depression and the insomnia."

• Tip...
• Taken for 6 months to 1 year
• August 16, 2014

For Major Depressive Disorder "It has greatly improved my mood, and I have been sleeping wonderfully too."

• kou...
• Taken for 1 to 6 months
• June 5, 2015

For Depression "After about a week, it helped with anxiety, it is prescribed actually to me for insomnia, and I'm on 150 mg. Works well. I have tried about everything else."

• bob...
• December 31, 2019

For Anxiety "Sinequan didn't help my anxiety at all. I had a horrible experience with it in general on 25 mg, I believe tightness in my chest, and I got lightheaded. Don't take this med."