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Polythiazide Dosage

Applies to the following strengths: 1 mg; 2 mg; 4 mg

Usual Adult Dose for Edema

Initial dose: 1 mg orally once a day.

Usual Adult Dose for Hypertension

Initial dose: 1 mg orally once a day.

Renal Dose Adjustments

CrCl < 25 mL/min: Not recommended.

Liver Dose Adjustments

Data not available

Dose Adjustments

The dose may be titrated as necessary once a week.


Polythiazide is not recommended for patients with liver disease.


Data not available

Other Comments

The maximum dose is 4 mg per day.

Periodic monitoring of electrolytes is recommended, particularly in elderly patients and in patients receiving a high dose.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.