Polythiazide use while Breastfeeding
Drugs containing Polythiazide: Renese, Minizide, Renese-R
Polythiazide Levels and Effects while Breastfeeding
Summary of Use during Lactation
If polythiazide is required by the mother, it is not a reason to discontinue breastfeeding. Intense diuresis with large doses may decrease breastmilk production.
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Polythiazide 2 mg was given twice daily for 8 days beginning within 24 hours of delivery to suppress postpartum lactation. Patients also had breast binding for at least 10 days and fluid restriction. The authors reported that this technique was effective in 124 cases reviewed. There are no data on the effects of diuretics on established lactation.
Alternate Drugs to Consider
1. Timmermans HL. [Use of P 2525 or polythiazide as suppressor of lactation during post-partum]. Brux Med. 1963;43:1051-6. PMID: 14095820
CAS Registry Number
LactMed Record Number
Last Revision Date
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