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Polythiazide / Prazosin Dosage

Applies to the following strengths: 0.5 mg-1 mg; 0.5 mg-2 mg; 0.5 mg-5 mg

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Hypertension

Initial dose: 1 capsule of (polythiazide-prazosin 0.5 mg/1 mg) 2-3 times a day. Determine dosage by individual titration.
Maintenance dose: May increase up to a maximum of 2 capsules of (polythiazide-prazosin 0.5 mg/5 mg) twice a day.

Dose Adjustments

The dose may be titrated as necessary once a week.


Thiazide diuretics should be used with caution in patients with severe renal disease and/or hepatic impairment.


Prazosin is not dialyzable because it is protein bound.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.