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Antiadrenergic agents (peripheral) with thiazides

What are Antiadrenergic agents (peripheral) with thiazides?

Alpha adrenoreceptor antagonists prevent the stimulation of alpha-adrenergic receptors at the nerve endings of the sympathetic nervous system. Alpha1-selective antagonists are used as cardiovascular agents as they block the alpha adrenoreceptors on the vascular smooth muscle and widen the arteries, causing vasodilatation and a reduction in blood pressure. Thiazide diuretics decrease active re-absorption of sodium and chloride ions by inhibiting the sodium/chloride co-transporter in the distal convoluted tubule. They also increase potassium ion loss. Thiazide diuretics decrease the blood volume by diuresis and are used to decrease blood pressure. The combination of a peripherally acting antiadrenergic agents with thiazide diuretics is used to treat hypertension.

Types of Antiadrenergic agents (peripheral) with thiazides

Please refer to the drug classes listed below for further information.

Medical conditions associated with antiadrenergic agents (peripheral) with thiazides:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.