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Lipofen Dosage

Generic name: FENOFIBRATE 50mg
Dosage form: capsule
Drug class: Fibric acid derivatives

Medically reviewed by Drugs.com. Last updated on Jun 18, 2025.

Prior to Initiation of LIPOFEN

  • Assess lipid levels before initiating therapy. Identify other causes (e.g., diabetes mellitus, hypothyroidism, or medications) of high TG levels and manage as appropriate.
  • Patients should be placed on an appropriate lipid-lowering diet before receiving LIPOFEN, and should continue this diet during treatment with LIPOFEN.
  • In patients with diabetes and fasting chylomicronemia, improve glycemic control prior to considering starting LIPOFEN.

Recommended Dosage and Administration

  • Severe hypertriglyceridemia:
    • The recommended dosage of LIPOFEN is 50 mg or 150 mg orally once daily.
    • Dosage should be individualized according to patient response, and should be adjusted if necessary following repeat lipid determinations at 4 to 8 week intervals.
  • Primary hyperlipidemia:
    • The recommended dosage of LIPOFEN is 150 mg orally once daily.
  • Administer LIPOFEN as a single dose at any time of day, with food.
  • Advise patients to swallow LIPOFEN capsules whole. Do not crush, break, dissolve, or chew capsules.
  • Assess TG when clinically appropriate, as early as 4 to 8 weeks after initiating LIPOFEN. Discontinue LIPOFEN in patients who do not have an adequate response after 2 months of treatment.
  • If a dose is missed, advise patients not to take an extra dose. Resume treatment with the next dose.
  • Advise patients to take LIPOFEN at least 1 hour before or 4 hours to 6 hours after a bile acid binding resin to avoid impeding its absorption.

Recommended Dosage in Patients with Renal Impairment

  • Assess renal function prior to initiation of LIPOFEN and periodically thereafter.
  • Treatment with LIPOFEN should be initiated at a dosage of 50 mg orally once daily in patients with mild to moderately impaired renal function (eGFR 30 to <60 mL/min/1.73m2), and increased only after evaluation of the effects on renal function and TG levels at this dosage.
  • LIPOFEN is contraindicated in patients with severe renal impairment (eGFR <30 mL/min/1.73m2), including those with end-stage renal disease (ESRD) and those receiving dialysis.

Recommended Dosage in Geriatric Patients

Dosage selection for geriatric patients should be made on the basis of renal function.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.