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Fluocinolone Ophthalmic Dosage

Medically reviewed by Drugs.com. Last updated on Nov 15, 2018.

Applies to the following strengths: 0.59 mg; 0.19 mg; 0.18 mg

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Uveitis

1 implant, containing 1 tablet of 0.59 mg of fluocinolone acetonide, to be surgically implanted into the posterior segment of the affected eye through a pars plana incision

Comments:
-Following depletion of this drug as evidenced by recurrence of uveitis, the implant may be replaced.
-Caution should be used in handling the implant to avoid damage, which may result in an increased rate of drug release from the implant.
-Care should be taken during implantation and explantation to avoid sheer forces on the implant that could disengage the silicone cup reservoir from the suture tab.
-Aseptic technique should be maintained at all times prior to and during the surgical implantation procedure.
-The implant should not be resterilized by any method.

Use: Treatment of chronic non-infectious uveitis affecting the posterior segment of the eye

Usual Adult Dose for Macular Edema

1 implant, containing 0.19 mg of fluocinolone acetonide, to be surgically implanted inferior to the optic disc and posterior to the equator of the eye

Comments:
-For ophthalmic intravitreal injection.
-Aseptic technique should be maintained at all times prior to and during the surgical implantation procedure. Consult the manufacturer product information for proper handling.
-Patients should be monitored for elevation in intraocular pressure and for endophthalmitis.
-Patients should be instructed to report any symptoms suggestive of endophthalmitis.

Use: Treatment of diabetic macular edema in patients who have been previously treated with a course of corticosteroids and did not have a clinically significant rise in intraocular pressure.

Usual Pediatric Dose for Uveitis

12 years or older:
1 implant, containing 1 tablet of 0.59 mg of fluocinolone acetonide, to be surgically implanted into the posterior segment of the affected eye through a pars plana incision

Comments:
-Following depletion of this drug as evidenced by recurrence of uveitis, the implant may be replaced.
-Caution should be used in handling the implant to avoid damage, which may result in an increased rate of drug release from the implant.
-Care should be taken during implantation and explantation to avoid sheer forces on the implant that could disengage the silicone cup reservoir from the suture tab.
-Aseptic technique should be maintained at all times prior to and during the surgical implantation procedure.
-The implant should not be resterilized by any method.

Use: Treatment of chronic non-infectious uveitis affecting the posterior segment of the eye

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

0.19 mg intravitreal implant: Safety and efficacy have not been established in patients younger than 18 years.

0.59 mg intravitreal implant: Safety and efficacy have not been established in patients younger than 12 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-The manufacturer product information should be consulted.

Storage requirements:
-Do not refrigerate or freeze.
-Do not open the sealed tray until just before application

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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