Clofibrate Dosage
Applies to the following strengths: 500 mg
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Hyperlipidemia
500 mg orally 4 times a day.
Renal Dose Adjustments
CrCl < 10 mL/min: Not recommended.
CrCl 10 to 50 mL/min: 500 mg orally every 12 to 18 hours.
CrCl > 50 mL/min: 500 mg orally every 6 to 12 hours.
Liver Dose Adjustments
Clofibrate is considered contraindicated in patients with significant hepatic dysfunction.
Precautions
It is contraindicated in patients with clinically significant hepatic dysfunction.
Dialysis
Clofibrate has been shown to have an average elimination half-life of 133 hours in patients undergoing hemodialysis.
Other Comments
Some patients may respond to lower doses.
More about clofibrate
- Check interactions
- Compare alternatives
- Side effects
- During pregnancy
- Drug class: fibric acid derivatives
Patient resources
Related treatment guides
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.