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Chlorthalidone / Clonidine Dosage

Applies to the following strengths: 15 mg-0.1 mg; 15 mg-0.2 mg; 15 mg-0.3 mg

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Hypertension

Chlorthalidone 15 mg-Clonidine 0.1 to 0.3 mg orally once or twice a day

Maximum dose: Chlorthalidone 30 mg-Clonidine 0.6 mg orally per day

Use: Treatment of hypertension when the desired effect has not been achieved with monotherapy or as substitution for the titrated individual components.

Renal Dose Adjustments

Use with caution

Liver Dose Adjustments

Use with caution


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments


  • Metabolic: Serum electrolytes prior to starting treatment and periodically thereafter.

Patient advice:
  • Caution patients against interruption of this drug without a physician's advice.
  • Advise patients who engage in potentially hazardous activities, such as operating machinery or driving, of a potential sedative effect of clonidine.
  • Encourage patients to contact their physician if they experience any symptoms of potassium loss (e.g., excess thirst, tiredness, drowsiness, restlessness, muscle pains or cramps, nausea, vomiting, or increased heart rate).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.