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Aloxi Dosage

Generic name: PALONOSETRON HYDROCHLORIDE 0.25mg in 5mL
Dosage form: injection

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Medically reviewed on December 1, 2017.

Recommended Dosing

Chemotherapy-Induced Nausea and Vomiting

Age Dose* Infusion Time
Adults 0.25 mg x 1

Infuse over 30 seconds beginning approx.
30 min before the start of chemo

(1 month to less than 17 years)

20 micrograms per
kilogram (max 1.5 mg) x 1

Infuse over 15 minutes beginning approx.
30 min before the start of chemo

*Note different dosing units in pediatrics

Postoperative Nausea and Vomiting
Dosage for Adults - a single 0.075 mg intravenous dose administered over 10 seconds immediately before the induction of anesthesia.

Instructions for Intravenous Administration

ALOXI is supplied ready for intravenous administration at a concentration of 0.05 mg/mL (50 mcg/ mL). ALOXI should not be mixed with other drugs. The infusion line should be flushed with normal saline before and after administration of ALOXI. Parenteral drug products should be inspected visually for particulate matter and discoloration before administration, whenever solution and container permit.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.