Qelbree Disease Interactions
There are 4 disease interactions with Qelbree (viloxazine).
Antidepressants (applies to Qelbree) mania
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Bipolar Disorder
All antidepressants may occasionally cause mania or hypomania, particularly in patients with bipolar disorder. Therapy with antidepressants should be administered cautiously in patients with a history of mania/hypomania.
Viloxazine (applies to Qelbree) depression
Moderate Potential Hazard, Moderate plausibility.
Patients being treated with viloxazine should be monitored for clinical worsening and emergence of suicidal thoughts and behaviors. In clinical trials, higher rates of suicidal thoughts and behavior were reported in pediatric patients with attention deficit hyperactivity disorder (ADHD) receiving this drug than placebo. Prior to initiating treatment, patients should be screened for a personal or family history of suicide, bipolar disorder, and depression.
Viloxazine (applies to Qelbree) liver impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
The effect of hepatic impairment on the pharmacokinetics of viloxazine is unknown. Viloxazine is not recommended in patients with hepatic impairment.
Viloxazine (applies to Qelbree) renal impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
The exposure of viloxazine increases in patients with renal impairment. Dose reduction is recommended in patients with severe renal impairment (estimated glomerular filtration rate less than 30 mL/min/1.73 m3).
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Qelbree drug interactions
There are 283 drug interactions with Qelbree (viloxazine).
Qelbree alcohol/food interactions
There is 1 alcohol/food interaction with Qelbree (viloxazine).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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