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WP Thyroid Disease Interactions

There are 5 disease interactions with WP Thyroid (thyroid desiccated).

Major

Thyroid hormones (applies to WP Thyroid) adrenal insufficiency

Major Potential Hazard, High plausibility.

The use of thyroid hormones is contraindicated in patients with uncorrected adrenal insufficiency. Thyroid hormones increase tissue demand for adrenocortical hormones and may precipitate acute adrenal crisis. In patients with controlled adrenal insufficiency or other endocrine disorders, therapy for these concomitant disorders may need to be adjusted following thyroid replacement, since hypothyroidism often obscure or diminish the signs and symptoms of these conditions. Clinical monitoring of thyroid and adrenal function as well as any other appropriate endocrine function is recommended during thyroid hormone therapy.

References

  1. "Product Information. Synthroid (levothyroxine)." Abbott Pharmaceutical PROD (2002):
  2. "Product Information. Cytomel (liothyronine)." Monarch Pharmaceuticals Inc PROD (2001):
  3. "Product Information. Armour Thyroid (thyroid desiccated)." Forest Pharmaceuticals (2022):
  4. "Product Information. Thyrolar (liotrix)." Forest Pharmaceuticals PROD (2001):
View all 4 references
Major

Thyroid hormones (applies to WP Thyroid) cardiovascular disease

Major Potential Hazard, High plausibility. Applicable conditions: Hypertension, Heart Disease

Thyroid hormones cause increases in myocardial contractility and heart rate as a result of increased metabolic demands and oxygen consumption. Therapy with thyroid hormones should be administered cautiously and initiated at reduced dosages in patients with cardiovascular disorders such as angina, coronary artery disease, and hypertension. Clinical monitoring of cardiovascular function is recommended. If chest pain or exacerbation of cardiovascular disease occurs, the dosage of thyroid hormone should be reduced, even at the expense of achieving euthyroid state. Thyroid hormones should not be administered to patients with an acute myocardial infarction that is not complicated by hypothyroidism.

References

  1. "Product Information. Synthroid (levothyroxine)." Abbott Pharmaceutical PROD (2002):
  2. "Product Information. Cytomel (liothyronine)." Monarch Pharmaceuticals Inc PROD (2001):
  3. "Product Information. Armour Thyroid (thyroid desiccated)." Forest Pharmaceuticals (2022):
  4. "Product Information. Thyrolar (liotrix)." Forest Pharmaceuticals PROD (2001):
View all 4 references
Major

Thyroid hormones (applies to WP Thyroid) thyrotoxicosis

Major Potential Hazard, High plausibility. Applicable conditions: Hyperthyroidism

The use of thyroid hormones is contraindicated in patients with untreated thyrotoxicosis of any etiology, since thyroid hormones may exacerbate the condition.

References

  1. "Product Information. Synthroid (levothyroxine)." Abbott Pharmaceutical PROD (2002):
  2. "Product Information. Cytomel (liothyronine)." Monarch Pharmaceuticals Inc PROD (2001):
  3. "Product Information. Armour Thyroid (thyroid desiccated)." Forest Pharmaceuticals (2022):
  4. "Product Information. Thyrolar (liotrix)." Forest Pharmaceuticals PROD (2001):
View all 4 references
Moderate

Thyroid hormones (applies to WP Thyroid) diabetes

Moderate Potential Hazard, High plausibility. Applicable conditions: Diabetes Insipidus, Diabetes Mellitus

Since hypothyroidism often obscure or diminish the signs and symptoms of endocrine disorders such as diabetes mellitus or diabetes insipidus, thyroid replacement therapy may aggravate the intensity of symptoms associated with these conditions. Patients with endocrine disorders should be monitored more closely during thyroid hormone therapy, and their medication regimen adjusted accordingly. If thyroid medication is later discontinued, a downward readjustment of insulin or oral hypoglycemic agent may be necessary in patients with diabetes mellitus to avoid hypoglycemia.

References

  1. "Product Information. Synthroid (levothyroxine)." Abbott Pharmaceutical PROD (2002):
  2. "Product Information. Cytomel (liothyronine)." Monarch Pharmaceuticals Inc PROD (2001):
  3. "Product Information. Armour Thyroid (thyroid desiccated)." Forest Pharmaceuticals (2022):
  4. "Product Information. Thyrolar (liotrix)." Forest Pharmaceuticals PROD (2001):
View all 4 references
Moderate

Thyroid hormones (applies to WP Thyroid) seizures

Moderate Potential Hazard, Low plausibility.

Thyroid hormones may alter the seizure threshold. Seizures have been reported rarely following the initiation of levothyroxine therapy. Therapy with thyroid hormones should be administered cautiously in patients predisposed to seizures.

References

  1. "Product Information. Synthroid (levothyroxine)." Abbott Pharmaceutical PROD (2002):

WP Thyroid drug interactions

There are 203 drug interactions with WP Thyroid (thyroid desiccated).

WP Thyroid alcohol/food interactions

There are 3 alcohol/food interactions with WP Thyroid (thyroid desiccated).


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.