Zanosar (streptozocin) Disease Interactions
There are 2 disease interactions with Zanosar (streptozocin):
Streptozocin (Includes Zanosar) ↔ Hepatic Dysfunction
Severe Potential Hazard, Low plausibility
Applies to: Liver Disease
Unspecified hepatic dysfunction has been noted during streptozocin therapy. The pharmacokinetic disposition of streptozocin has not been extensively studied. Therapy with streptozocin should be administered cautiously in patients with a history or predisposition to compromised hepatic function. Liver function tests should be done at least weekly and dosage adjustments or discontinuance of therapy may be indicated, depending upon the degree of toxicity noted.
- "Product Information. Zanosar (streptozocin)." Pharmacia and Upjohn, Kalamazoo, MI.
Streptozocin (Includes Zanosar) ↔ Diabetes
Moderate Potential Hazard, Moderate plausibility
Applies to: Diabetes Mellitus
Mild to moderate abnormalities of glucose tolerance have been noted in some patients treated with streptozocin. These have generally been reversible, but insulin shock with hypoglycemia has been observed. Caution is recommended when using this agent in diabetic patients, and close monitoring of blood sugar levels is recommended during therapy.
Zanosar (streptozocin) drug Interactions
There are 208 drug interactions with Zanosar (streptozocin)
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.
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