Zanosar Side Effects

Generic name: streptozocin

Medically reviewed by Drugs.com. Last updated on May 28, 2024.

Note: This document provides detailed information about Zanosar Side Effects associated with streptozocin. Some dosage forms listed on this page may not apply specifically to the brand name Zanosar.

Applies to streptozocin: intravenous powder for solution.

Precautions

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for any unwanted effects.

While you are being treated with streptozocin (the active ingredient contained in Zanosar) and after you stop treatment with it, do not have any immunizations (vaccinations) without your doctor's approval. Streptozocin may lower your body's resistance and there is a chance you might get the infection the immunization is meant to prevent. In addition, other people living in your household should not take oral polio vaccine since there is a chance they could pass the polio virus on to you. Also, avoid persons who have recently taken oral polio vaccine. Do not get close to them and do not stay in the same room with them for very long. If you cannot take these precautions, you should consider wearing a protective face mask that covers the nose and mouth.

If streptozocin accidentally seeps out of the vein into which it is injected, it may damage some tissues and cause scarring. Tell the health care professional right away if you notice redness, pain, or swelling at the place of injection.

Along with their needed effects, medicines like streptozocin can sometimes cause unwanted effects such as kidney problems and other side effects. These and others are described below. Also, because of the way these medicines act on the body, there is a chance that they might cause other unwanted effects that may not occur until months or years after the medicine is used. These delayed effects may include certain types of cancer, such as leukemia. Streptozocin has been shown to cause tumors (some cancerous) in animals. Discuss these possible effects with your doctor.

Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking streptozocin:

Check with your doctor immediately if any of the following side effects occur while taking streptozocin:

Check with your doctor as soon as possible if any of the following side effects occur while taking streptozocin:

Other side effects of Zanosar

Some side effects of streptozocin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, Check with your doctor immediately if you notice the following side effects:

For healthcare professionals

Applies to streptozocin: intravenous powder for injection.

Renal adverse events

• Frequency not reported: Renal toxicity (azotemia, anuria, hypophosphatemia, glycosuria, renal tubular acidosis), nephrogenic diabetes insipidus^[Ref]

Hepatic

• Frequency not reported: Hepatic toxicity (elevated SGOT and LDH levels, hypoalbuminemia)^[Ref]

Gastrointestinal

• Frequency not reported: Nausea, vomiting, diarrhea^[Ref]

Hematologic

• Rare (less than 0.1%): Hematologic toxicity (decreased hematocrit values, reduced leukocyte and platelet count)^[Ref]

Metabolic

• Frequency not reported: Glucose tolerance abnormalities, insulin shock, hypoglycemia^[Ref]

Local

• Postmarketing reports: Local inflammation^[Ref]

Psychiatric

• Frequency not reported: Confusion, lethargy, depression^[Ref]

See also:

Further information

Zanosar side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer