Zanosar Side Effects
Generic Name: streptozocin
Note: This page contains side effects data for the generic drug streptozocin. It is possible that some of the dosage forms included below may not apply to the brand name Zanosar.
For the Consumer
Applies to streptozocin: intravenous powder for solution
Along with their needed effects, medicines like streptozocin (the active ingredient contained in Zanosar) can sometimes cause unwanted effects such as kidney problems and other side effects. These and others are described below. Also, because of the way these medicines act on the body, there is a chance that they might cause other unwanted effects that may not occur until months or years after the medicine is used. These delayed effects may include certain types of cancer, such as leukemia. Streptozocin has been shown to cause tumors (some cancerous) in animals. Discuss these possible effects with your doctor.
Although not all of these side effects may occur, if they do occur they may need medical attention.
If any of the following side effects occur while taking streptozocin, check with your doctor immediately:Less common:
- Anxiety, nervousness, or shakiness
- chills, cold sweats, or cool, pale skin
- drowsiness or unusual tiredness or weakness
- fast pulse
- pain or redness at place of injection
- unusual hunger
If any of the following side effects occur while taking streptozocin, check with your doctor immediately:Rare:
- Black, tarry stools
- blood in urine or stools
- cough or hoarseness
- fever or chills
- lower back or side pain
- painful or difficult urination
- pinpoint red spots on skin
- unusual bleeding or bruising
If any of the following side effects occur while taking streptozocin, check with your doctor or nurse as soon as possible:More common:
- Swelling of feet or lower legs
- unusual decrease in urination
Some streptozocin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:More common:
- Nausea and vomiting (usually occurs within 2 to 4 hours after receiving dose and may be severe)
Side Effects: Post Treatment
After you stop taking this drug, it is possible that you may still experience side effects that need medical attention. If you notice any of the following side effects check with your doctor immediately:More common:
- Decrease in urination
- swelling of feet or lower legs
For Healthcare Professionals
Applies to streptozocin: intravenous powder for injection
Frequency not reported: Renal toxicity (azotemia, anuria, hypophosphatemia, glycosuria, renal tubular acidosis), nephrogenic diabetes insipidus[Ref]
Frequency not reported: Hepatic toxicity (elevated SGOT and LDH levels, hypoalbuminemia)[Ref]
Frequency not reported: Nausea, vomiting, diarrhea[Ref]
Rare (less than 0.1%): Hematologic toxicity (decreased hematocrit values, reduced leukocyte and platelet count)[Ref]
Frequency not reported: Glucose tolerance abnormalities, insulin shock, hypoglycemia[Ref]
Postmarketing reports: Local inflammation[Ref]
Frequency not reported: Confusion, lethargy, depression[Ref]
1. "Product Information. Zanosar (streptozocin)." Pharmacia and Upjohn, Kalamazoo, MI.
It is possible that some side effects of Zanosar may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
More about Zanosar (streptozocin)
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