MiraLAX Disease Interactions
There are 3 disease interactions with MiraLAX (polyethylene glycol 3350).
Laxatives (applies to MiraLAX) inflammatory bowel disease
Major Potential Hazard, Moderate plausibility.
The use of laxatives is contraindicated in patients with inflammatory bowel disease. Patients with inflammatory bowel disease may experience colonic perforation with use of stimulant laxatives.
References (6)
- (2001) "Product Information. Dulcolax (bisacodyl)." Ciba Self-Medication Inc
- "Product Information. Fleet Bisacodyl (bisacodyl)." Fleet
- "Product Information. Kondremul Plain (mineral oil)." Bristol-Myers Squibb
- (2001) "Product Information. Neoloid (castor oil)." Paddock Laboratories Inc
- (2022) "Product Information. SenoSol-X (senna)." Apothecon Inc
- (2010) "Product Information. Suprep Bowel Prep Kit (magnesium/potassium/sodium sulfates)." Braintree Laboratories
Laxatives (applies to MiraLAX) intestinal obstruction disorders
Major Potential Hazard, Moderate plausibility. Applicable conditions: Gastrointestinal Obstruction
The use of laxatives is contraindicated in patients with intestinal obstruction disorders. Patients with intestinal obstruction disorders may need their underlying condition treated to correct the constipation. Some laxatives require reduction in the colon to their active form to be effective which may be a problem in patients with intestinal obstruction.
References (8)
- (2001) "Product Information. Dulcolax (bisacodyl)." Ciba Self-Medication Inc
- "Product Information. Fleet Bisacodyl (bisacodyl)." Fleet
- "Product Information. Kondremul Plain (mineral oil)." Bristol-Myers Squibb
- (2001) "Product Information. Fleet Mineral Oil Enema (mineral oil)." Fleet
- (2001) "Product Information. Citrucel (methylcellulose)." SmithKline Beecham
- (2001) "Product Information. Fleet Babylax (glycerin)." Alcon Laboratories Inc
- (2022) "Product Information. SenoSol-X (senna)." Apothecon Inc
- (2010) "Product Information. Suprep Bowel Prep Kit (magnesium/potassium/sodium sulfates)." Braintree Laboratories
PEG solutions (applies to MiraLAX) GI obstruction/perforation
Major Potential Hazard, Moderate plausibility. Applicable conditions: Gastrointestinal Obstruction, Gastrointestinal Perforation, Ulcerative Colitis
The use of polyethylene glycol (PEG) solutions is contraindicated in patients with gastrointestinal obstruction, perforation, or toxic megacolon. If gastrointestinal obstruction or perforation is suspected, appropriate studies should be performed prior to administration of these agents. Use with caution in patients with severe active ulcerative colitis. Increased activity of the gut caused by these agents could worsen these conditions.
References (4)
- Raymond PL (1991) "Mallory-Weiss tear associated with polyethylene glycol electrolyte lavage solution." Gastrointest Endosc, 37, p. 410-1
- McBride MA, Vanagunas A (1993) "Esophageal perforation associated with polyethylene glycol electrolyte lavage solution." Gastrointest Endosc, 39, p. 856-7
- "Product Information. Golytely (polyethylene glycol 3350 with electrolytes)." Braintree
- (2016) "Product Information. GlycoLax (polyethylene glycol 3350)." DispenseXpress Inc
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MiraLAX drug interactions
There are 222 drug interactions with MiraLAX (polyethylene glycol 3350).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
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Linzess
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Botox
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Bentyl
Bentyl is used to treat functional bowel or irritable bowel syndrome. Bentyl may also be used for ...
Xifaxan
Xifaxan (rifaximin) is used to treat travelers' diarrhea, irritable bowel syndrome with diarrhea ...
Dulcolax
Dulcolax (bisacodyl) is a laxative used to treat constipation. Includes Dulcolax side effects ...
Metamucil
Metamucil is used for constipation, dietary fiber supplementation, irritable bowel syndrome
Hyoscyamine
Hyoscyamine is used for anesthesia, anticholinesterase poisoning, crohn's disease, diverticulitis ...
Rifaximin
Rifaximin is used for crohn's disease, diarrhea, diarrhea, chronic, hepatic encephalopathy ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.