Diurex Water Capsules Disease Interactions
There is 1 disease interaction with Diurex Water Capsules (pamabrom).
Moderate
Pamabrom (applies to Diurex Water Capsules) hypokalemia
Moderate Potential Hazard, Moderate plausibility.
The use of pamabrom (a theobromine derivative) has been associated with the renal elimination of potassium due to its diuretic effects. Therapy with pamabrom should be administered cautiously in patients with hypokalemia.
References
- Niemeyer C, Hasenfub G, Wais U, et al. "Pharmacokinetics of hydrochlorothiazide in relation to renal function." Eur J Clin Pharmacol 24 (1983): 661-5
- "Product Information. Lozol (indapamide)." Rhone Poulenc Rorer (2002):
- "Product Information. Thalitone (chlorthalidone)." Monarch Pharmaceuticals Inc (2001):
- "Product Information. Minizide (polythiazide-prazosin)." Pfizer U.S. Pharmaceuticals
- "Product Information. Enduron (methyclothiazide)." Abbott Pharmaceutical (2001):
- "Product Information. Diucardin (hydroflumethiazide)." Wyeth-Ayerst Laboratories (2001):
- "Product Information. Exna (benzthiazide)." Wyeth-Ayerst Laboratories (2001):
Diurex Water Capsules drug interactions
There are 18 drug interactions with Diurex Water Capsules (pamabrom).
More about Diurex Water Capsules (pamabrom)
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Side effects
Drug class: miscellaneous diuretics
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
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