Mio-Rel Disease Interactions
There is 1 disease interaction with Mio-Rel (orphenadrine).
Orphenadrine (applies to Mio-Rel) anticholinergic effects
Major Potential Hazard, Moderate plausibility. Applicable conditions: Gastrointestinal Obstruction, Glaucoma/Intraocular Hypertension, Myasthenia Gravis, Urinary Retention, Esophageal Obstruction
Orphenadrine has mild anticholinergic activity, to which elderly patients are particularly sensitive. The manufacturer considers the use of orphenadrine to be contraindicated in patients with glaucoma, pyloric or duodenal obstruction, achalasia, prostatic hypertrophy, bladder neck obstruction, or myasthenia gravis. Orphenadrine should be used cautiously in other conditions that are likely to be exacerbated by anticholinergic activity, such as urinary retention and gastrointestinal obstructive disorders.
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Mio-Rel drug interactions
There are 399 drug interactions with Mio-Rel (orphenadrine).
Mio-Rel alcohol/food interactions
There is 1 alcohol/food interaction with Mio-Rel (orphenadrine).
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More about Mio-Rel (orphenadrine)
- Mio-Rel consumer information
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- Compare alternatives
- Latest FDA alerts (1)
- Side effects
- Dosage information
- During pregnancy
- Drug class: skeletal muscle relaxants
- Breastfeeding
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.