Ilevro Disease Interactions
There is 1 disease interaction with Ilevro (nepafenac ophthalmic).
NSAIDs (applies to Ilevro) asthma
Major Potential Hazard, High plausibility.
Nonsteroidal anti-inflammatory drugs (NSAIDs) are contraindicated in patients with history of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs; severe, sometimes fatal, anaphylactic reactions to NSAIDs have been reported in such patients. A subpopulation of patients with asthma may have aspirin-sensitive asthma which may include chronic rhinosinusitis complicated by nasal polyps, severe potentially fatal bronchospasm, and/or intolerance to aspirin and other NSAIDs. Since cross-reactivity between aspirin and other NSAIDs has been reported in such aspirin-sensitive patients, therapy with any NSAID should be avoided in patients with this form of aspirin sensitivity. NSAIDs should be used with caution in patients with preexisting asthma (without known aspirin sensitivity), and these patients should be monitored for changes in the signs and symptoms of asthma.
References
- "Product Information. Motrin (ibuprofen)." Pharmacia and Upjohn PROD (2002):
- "Product Information. Nalfon (fenoprofen)." Xspire Pharma PROD (2002):
- "Product Information. Indocin (indomethacin)." Merck & Co., Inc PROD (2002):
- "Product Information. Orudis (ketoprofen)." Wyeth-Ayerst Laboratories PROD (2002):
- "Product Information. Naprosyn (naproxen)." Syntex Laboratories Inc PROD (2002):
- "Product Information. Clinoril (sulindac)." Merck & Co., Inc PROD (2001):
- "Product Information. Tolectin (tolmetin)." McNeil Pharmaceutical PROD (2001):
- "Product Information. Voltaren (diclofenac)." Novartis Pharmaceuticals PROD (2001):
- "Product Information. Relafen (nabumetone)." SmithKline Beecham PROD (2001):
- "Product Information. Feldene (piroxicam)." Pfizer U.S. Pharmaceuticals PROD (2001):
- "Product Information. Ansaid (flurbiprofen)." Pharmacia and Upjohn PROD (2001):
- "Product Information. Lodine (etodolac)." Wyeth-Ayerst Laboratories PROD (2001):
- "Product Information. Daypro (oxaprozin)." Searle PROD (2001):
- "Product Information. Celebrex (celecoxib)." Searle PROD (2001):
- "Product Information. Mobic (meloxicam)." Boehringer-Ingelheim PROD (2001):
Ilevro drug interactions
There are 74 drug interactions with Ilevro (nepafenac ophthalmic).
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.