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Ilevro Side Effects

Generic Name: nepafenac ophthalmic

Note: This page contains information about the side effects of nepafenac ophthalmic. Some of the dosage forms included on this document may not apply to the brand name Ilevro.

For the Consumer

Applies to nepafenac ophthalmic: ophthalmic suspension

In addition to its needed effects, some unwanted effects may be caused by nepafenac ophthalmic (the active ingredient contained in Ilevro). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking nepafenac ophthalmic:

More common:
  • Blurred vision
  • change in vision
  • decrease in vision
  • loss of vision
Less common:
  • Eye pain
  • itching of the eye
  • swelling and/or redness of the eye and lining of the eyelid

Minor Side Effects

Some of the side effects that can occur with nepafenac ophthalmic may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:
  • Feeling of having something in the eye
  • sticky sensation of the eyelids
Less common:
  • Change in color vision
  • cough
  • crusting in the corner of the eye
  • difficulty seeing at night
  • dizziness
  • dry eyes
  • fever
  • headache
  • increased sensitivity of the eyes to sunlight
  • nausea or vomiting
  • nervousness
  • pounding in the ears
  • seeing flashes or sparks of light
  • seeing floating spots before the eyes, or a veil or curtain appearing across part of vision
  • slow or fast heartbeat
  • stuffy or runny nose
  • tenderness around the eyes and cheekbones
  • tightness of the chest or wheezing
  • troubled breathing

For Healthcare Professionals

Applies to nepafenac ophthalmic: ophthalmic suspension


Common (1% to 10%): Capsular opacity, reduced visual acuity, foreign body sensation in the eyes, increased intraocular pressure, sticky sensation, conjunctival edema, corneal edema, dry eye, ocular discomfort, photophobia, vitreous detachment
Uncommon (0.1% to 1%): Keratitis, punctate keratitis, corneal epithelium defect, eyelid margin crusting
Rare (less than 0.1%): Iritis, choroidal effusion, corneal deposits, eye pain, ocular hyperemia, blepharitis, eye pruritus, eye discharge, allergic conjunctivitis, increased lacrimation, conjunctival hyperemia
Frequency not reported: Corneal perforation, impaired healing (cornea), corneal opacity, corneal scar, eye irritation, eye swelling, ulcerative keratitis, corneal thinning, blurred vision[Ref]


Common (1% to 10%): Hypertension[Ref]


Common (1% to 10%): Nausea, vomiting[Ref]


Common (1% to 10%): Sinusitis[Ref]


Rare (less than 0.1%): Cutis laxa (dermatochalasis), allergic dermatitis[Ref]


The most commonly reported side effects were capsular opacity, decreased visual acuity, foreign body sensation, increased intraocular pressure, and sticky sensation.[Ref]


Rare (less than 0.1%): Hypersensitivity[Ref]

Nervous system

Rare (less than 0.1%): Dizziness[Ref]


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. "Product Information. Nevanac (nepafenac ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.

Not all side effects for Ilevro may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.