Misoprostol Disease Interactions
There are 2 disease interactions with misoprostol.
Misoprostol (applies to misoprostol) cardiovascular disease
Moderate Potential Hazard, Moderate plausibility.
Caution should be employed when administering misoprostol to patients with preexisting cardiovascular disease.
References (1)
- (2001) "Product Information. Cytotec (misoprostol)." Searle
Misoprostol (applies to misoprostol) diarrhea
Moderate Potential Hazard, High plausibility. Applicable conditions: Inflammatory Bowel Disease, Dehydration
Diarrhea may occur in up to 40% of patients receiving misoprostol. Misoprostol should be administered cautiously in patients with underlying conditions such as inflammatory bowel disease and dehydration. Careful monitoring during therapy is recommended.
References (2)
- Wildeman RA (1987) "Focus on misoprostol: review of worldwide safety data." Clin Invest Med, 10, p. 243-5
- (2001) "Product Information. Cytotec (misoprostol)." Searle
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Misoprostol drug interactions
There are 15 drug interactions with misoprostol.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
