Skip to main content

Milk of Magnesia Disease Interactions

There are 3 disease interactions with Milk of Magnesia (magnesium hydroxide).

Major

Laxatives (applies to Milk of Magnesia) inflammatory bowel disease

Major Potential Hazard, Moderate plausibility.

The use of laxatives is contraindicated in patients with inflammatory bowel disease. Patients with inflammatory bowel disease may experience colonic perforation with use of stimulant laxatives.

References

  1. "Product Information. Dulcolax (bisacodyl)." Ciba Self-Medication Inc PROD (2001):
  2. "Product Information. Fleet Bisacodyl (bisacodyl)." Fleet PROD
  3. "Product Information. Kondremul Plain (mineral oil)." Bristol-Myers Squibb PROD
  4. "Product Information. Neoloid (castor oil)." Paddock Laboratories Inc PROD (2001):
  5. "Product Information. SenoSol-X (senna)." Apothecon Inc (2022):
  6. "Product Information. Suprep Bowel Prep Kit (magnesium/potassium/sodium sulfates)." Braintree Laboratories (2010):
View all 6 references
Major

Laxatives (applies to Milk of Magnesia) intestinal obstruction disorders

Major Potential Hazard, Moderate plausibility. Applicable conditions: Gastrointestinal Obstruction

The use of laxatives is contraindicated in patients with intestinal obstruction disorders. Patients with intestinal obstruction disorders may need their underlying condition treated to correct the constipation. Some laxatives require reduction in the colon to their active form to be effective which may be a problem in patients with intestinal obstruction.

References

  1. "Product Information. Dulcolax (bisacodyl)." Ciba Self-Medication Inc PROD (2001):
  2. "Product Information. Fleet Bisacodyl (bisacodyl)." Fleet PROD
  3. "Product Information. Kondremul Plain (mineral oil)." Bristol-Myers Squibb PROD
  4. "Product Information. Fleet Mineral Oil Enema (mineral oil)." Fleet PROD (2001):
  5. "Product Information. Citrucel (methylcellulose)." SmithKline Beecham PROD (2001):
  6. "Product Information. Fleet Babylax (glycerin)." Alcon Laboratories Inc PROD (2001):
  7. "Product Information. SenoSol-X (senna)." Apothecon Inc (2022):
  8. "Product Information. Suprep Bowel Prep Kit (magnesium/potassium/sodium sulfates)." Braintree Laboratories (2010):
View all 8 references
Major

Magnesium salts (applies to Milk of Magnesia) renal dysfunction

Major Potential Hazard, High plausibility.

Magnesium is eliminated by the kidney. The serum concentration of magnesium is increased in patients with renal impairment. Magnesium toxicity includes CNS depression, muscular paralysis, respiratory depression, hypotension and prolonged cardiac conduction time. Disappearance of the patellar reflex is a useful clinical sign of magnesium intoxication. Therapy with magnesium should be administered cautiously and dosages should be modified in patients with compromised renal function. Clinical monitoring of serum magnesium levels is recommended.

References

  1. "Product Information. Mag-Ox 400 (magnesium oxide)." Blaine Company Inc. PROD (2001):
  2. "Product Information. Uro-Mag (magnesium oxide)." Blaine Company Inc. PROD (2001):
  3. "Product Information. Slow-Mag (magnesium chloride)." Searle PROD (2001):
  4. "Product Information. Magonate (magnesium gluconate)." Fleming and Company PROD (2001):
  5. "Product Information. Losospan (magaldrate)." Whitehall-Robbins PROD (2001):
View all 5 references

Milk of Magnesia drug interactions

There are 408 drug interactions with Milk of Magnesia (magnesium hydroxide).


Report options

Loading...
QR code containing a link to this page

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.