Odactra Disease Interactions

The use of allergen immunotherapy, such as mixed grass pollens, ragweed pollen, house dust mite allergen extract, and timothy grass pollen allergen extracts may cause severe allergic reactions such as anaphylaxis and laryngopharyngeal edema. These agents are contraindicated in patients with severe, unstable or uncontrolled asthma, a history of any severe systemic allergic reaction, and a history of any severe local reaction to sublingual allergen immunotherapy as these conditions could compromise breathing and be life-threatening.

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The use of allergen immunotherapy, such as mixed grass pollens, ragweed pollen, house dust mite allergen extract, and timothy grass pollen allergen extracts, is contraindicated in patients with a history of eosinophilic esophagitis. This condition could compromise swallowing, lead to food impaction, vomiting, and heartburn which may cause permanent damage to the esophagus.

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The use of house dust mite allergen extract is contraindicated in patients with autoimmune disease due to the possibility of routine immunizations exacerbating symptoms of the underlying disease.

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The use of house dust mite allergen extract is contraindicated in patients with diseases characterized by a bleeding diathesis.

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The use of house dust mite allergen extract is contraindicated in patients who have experienced a recent myocardial infarction as these patients may not be able to tolerate immunotherapy. The benefit-to-risk ratio must be carefully evaluated before deciding to initiate such treatment.

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The use of house dust mite allergen extract is contraindicated in children with nephrotic syndrome due to a variety of seemingly unrelated events that may cause an exacerbation of nephrotic disease.

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The use of allergen immunotherapy, such as mixed grass pollens, ragweed pollen, house dust mite allergen extract, and timothy grass pollen allergen extracts may not be suitable for patients with certain medical conditions that may reduce the ability to survive a serious allergic reaction or increase the risk of adverse reactions after epinephrine administration. Examples of these medical conditions include but are not limited to markedly compromised lung function (either chronic or acute), unstable angina, recent myocardial infarction, significant arrhythmia, and uncontrolled hypertension. It is recommended to exercise care in these patients.

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