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Fosaprepitant Disease Interactions

There is 1 disease interaction with fosaprepitant.

Moderate

Fosaprepitant (applies to fosaprepitant) severe hepatic impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

There are no clinical or pharmacokinetic data in patients with severe liver dysfunction (Child-Pugh score greater than 9); therefore, caution and additional monitoring for adverse reactions are recommended when using fosaprepitant in these patients.

References

  1. "Product Information. Emend for Injection (fosaprepitant)." Merck Sharp & Dohme LLC SUPPL-21 (2022):

Fosaprepitant drug interactions

There are 430 drug interactions with fosaprepitant.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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