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Fexofenadine Disease Interactions

There is 1 disease interaction with fexofenadine.


Fexofenadine (applies to fexofenadine) renal dysfunction

Moderate Potential Hazard, High plausibility.

Fexofenadine is primarily eliminated by the kidney, and the risk of toxic reactions may be greater in patients with renal impairment due to decreased drug clearance. Care should be taken in dose selection and it may be useful to monitor renal function.


  1. "Product Information. Allegra (fexofenadine)." Hoechst Marion Roussel (2001):
  2. Russell T, Stoltz M, Weir S "Pharmacokinetics, pharmacodynamics, and tolerance of single- and multiple-dose fexofenadine hydrochloride in healthy male volunteers." Clin Pharmacol Ther 64 (1998): 612-21

Fexofenadine drug interactions

There are 95 drug interactions with fexofenadine.

Fexofenadine alcohol/food interactions

There is 1 alcohol/food interaction with fexofenadine.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.