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Toviaz (fesoterodine) Disease Interactions

There are 6 disease interactions with Toviaz (fesoterodine):

Major

Fesoterodine (applies to Toviaz) GI retention

Major Potential Hazard, Moderate plausibility. Applicable conditions: Gastrointestinal Obstruction

The use of fesoterodine is contraindicated in patients with gastric retention. Fesoterodine is a competitive muscarinic receptor antagonist and exerts direct antispasmodic effects on smooth muscles. Caution is advised even when using this agent in patients with decreased gastrointestinal motility.

Major

Fesoterodine (applies to Toviaz) narrow-angle glaucoma

Major Potential Hazard, Moderate plausibility. Applicable conditions: Glaucoma (Narrow Angle)

The use of fesoterodine is contraindicated in patients with uncontrolled narrow-angle glaucoma. Fesoterodine is a competitive muscarinic receptor antagonist. Its use can result in increased intraocular pressure and loss of accommodation. Caution is advised even when using this agent in patients being treated for narrow-angle glaucoma.

Major

Fesoterodine (applies to Toviaz) urinary retention

Major Potential Hazard, Moderate plausibility.

The use of fesoterodine is contraindicated in patients with urinary retention. Fesoterodine is a competitive muscarinic receptor antagonist and exerts direct antispasmodic effects on smooth muscles. Caution is advised even when using this agent in patients with clinically significant bladder outlet obstruction because of the risk of urinary retention.

Moderate

Fesoterodine (applies to Toviaz) hepatic dysfunction

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

The use of fesoterodine has not been studied in patients with severe hepatic impairment and therefore is not recommended for use in this patient population. No dose adjustment is recommended in patients with mild or moderate hepatic impairment. Use caution when using this agent in patients with severe hepatic impairment.

Moderate

Fesoterodine (applies to Toviaz) myasthenia gravis

Moderate Potential Hazard, Moderate plausibility.

Fesoterodine is a competitive muscarinic receptor antagonist. Fesoterodine should be used with caution in patients with myasthenia gravis, a disease characterized by decreased cholinergic activity at the neuromuscular junction.

Moderate

Fesoterodine (applies to Toviaz) renal dysfunction

Moderate Potential Hazard, Moderate plausibility.

Doses of fesoterodine fumarate greater than 4 mg are not recommended in patients with severe renal impairment. No dose adjustment is recommended in patients with mild or moderate renal impairment.

Toviaz (fesoterodine) drug interactions

There are 277 drug interactions with Toviaz (fesoterodine)

Toviaz (fesoterodine) alcohol/food interactions

There is 1 alcohol/food interaction with Toviaz (fesoterodine)

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.