Clevidipine Disease Interactions
There are 4 disease interactions with clevidipine.
Clevidipine (applies to clevidipine) aortic stenosis
Major Potential Hazard, Moderate plausibility.
Clevidipine is contraindicated in patients with severe aortic stenosis because afterload reduction can be expected to reduce myocardial oxygen delivery.
Clevidipine (applies to clevidipine) lipid dysfunction
Major Potential Hazard, Moderate plausibility. Applicable conditions: Hyperlipidemia, Pancreatitis
Clevidipine is contraindicated in patients with defective lipid metabolism such as pathologic hyperlipemia, lipoid nephrosis, or acute pancreatitis if it is accompanied by hyperlipidemia.
Clevidipine (applies to clevidipine) heart failure
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Congestive Heart Failure
The use of clevidipine can produce negative inotropic effects and exacerbate heart failure. It is recommended to monitor heart failure patients carefully during treatment with this agent.
Clevidipine (applies to clevidipine) hypotension
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Tachyarrhythmia
The use of clevidipine may produce systemic hypotension and reflex tachycardia. Dosage reduction may be necessary. There is limited experience with short-duration therapy with beta-blockers as a treatment for clevidipine -induced tachycardia; therefore, beta-blocker use for this purpose is not recommended. Close monitoring is recommended.
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Clevidipine drug interactions
There are 259 drug interactions with clevidipine.
Clevidipine alcohol/food interactions
There are 3 alcohol/food interactions with clevidipine.
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- During pregnancy
- Drug class: calcium channel blockers
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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