Durysta Disease Interactions
There are 3 disease interactions with Durysta (bimatoprost ophthalmic).
Bimatoprost (applies to Durysta) renal/liver disease
Moderate Potential Hazard, Low plausibility. Applicable conditions: Renal Dysfunction
Topically applied bimatoprost is systemically absorbed, then rapidly metabolized by the liver and eliminated by the kidney. Bimatoprost has not been adequately studied in the treatment of patients with impaired renal and/or hepatic function. Therapy with bimatoprost ophthalmic solution should be administered cautiously in such patients.
References
- (2001) "Product Information. Lumigan (bimatoprost ophthalmic)." Allergan Inc
- (2009) "Product Information. Latisse (bimatoprost topical ophthalmic)." Allergan Inc
Ophthalmic PG analogues (applies to Durysta) macular edema
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Aphakia, Pseudophakia, Retinal Disorder
Macular edema, including cystoid macular edema, has been reported during treatment with ophthalmic prostaglandin analogues. Most cases occurred in patients with aphakia, pseudophakia with a torn posterior lens capsule, or known risk factors for macular edema (e.g., posterior uveitis, certain retinal disorders). Therapy with ophthalmic prostaglandin analogues should be administered cautiously in these patients.
References
- (2001) "Product Information. Xalatan (latanoprost ophthalmic)." Pharmacia and Upjohn
- (2001) "Product Information. Lumigan (bimatoprost ophthalmic)." Allergan Inc
- (2001) "Product Information. Travatan (travoprost ophthalmic)." Alcon Laboratories Inc
- (2009) "Product Information. Latisse (bimatoprost topical ophthalmic)." Allergan Inc
Ophthalmic PG analogues (applies to Durysta) uveitis
Moderate Potential Hazard, Moderate plausibility.
Bimatoprost, latanoprost, and travoprost are synthetic prostaglandin analogues. Theoretically, these agents may mimic endogenous prostaglandins and mediate ocular inflammatory responses. In clinical trials, uveitis and iritis have been reported rarely. Therapy with ophthalmic prostaglandin analogues should be administered cautiously in patients with active intraocular inflammation.
References
- (2001) "Product Information. Xalatan (latanoprost ophthalmic)." Pharmacia and Upjohn
- (2001) "Product Information. Lumigan (bimatoprost ophthalmic)." Allergan Inc
- (2001) "Product Information. Travatan (travoprost ophthalmic)." Alcon Laboratories Inc
Durysta drug interactions
There are 7 drug interactions with Durysta (bimatoprost ophthalmic).
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.