Zelboraf Alternatives Compared
| Zelboraf (vemurafenib) | Yervoy (ipilimumab) | Mekinist (trametinib) |
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| Zelboraf (vemurafenib) | Yervoy (ipilimumab) | Mekinist (trametinib) |
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Prescription only
Prescribed for Erdheim-Chester Disease, Melanoma - Metastatic. Zelboraf may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Melanoma - Metastatic, Renal Cell Carcinoma, Colorectal Cancer, Malignant Pleural Mesothelioma, Melanoma. Yervoy may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Melanoma - Metastatic, Low-Grade Glioma, Non Small Cell Lung Cancer, Solid Tumors, Thyroid Cancer. Mekinist may also be used for purposes not listed in this medication guide. |
Related suggestions Melanoma, Metastatic
Popular comparisons
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| More about Zelboraf (vemurafenib) | More about Yervoy (ipilimumab) | More about Mekinist (trametinib) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Zelboraf has an average rating of 6.3 out of 10 from a total of 4 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 25% reported a negative effect. |
Yervoy has an average rating of 9.5 out of 10 from a total of 2 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Mekinist has an average rating of 7.3 out of 10 from a total of 3 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 33% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
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View all Zelboraf side effects |
View all Yervoy side effects |
View all Mekinist side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Zelboraf prices |
View all Yervoy prices |
View all Mekinist prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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120 hours |
352.8 hours |
115.2 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 625 drugs are known to interact with Zelboraf:
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A total of 661 drugs are known to interact with Yervoy:
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A total of 33 drugs are known to interact with Mekinist:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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August 17, 2011 |
March 25, 2011 |
May 29, 2013 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.