Zelboraf Alternatives Compared
| Zelboraf Remove Zelboraf from your drug comparison | Yervoy Remove Yervoy from your drug comparison | Mekinist Remove Mekinist from your drug comparison |
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| Zelboraf vemurafenib Remove Zelboraf from your drug comparison | Yervoy ipilimumab Remove Yervoy from your drug comparison | Mekinist trametinib Remove Mekinist from your drug comparison | ||||||||||||||||||||||||
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Prescribed for Erdheim-Chester Disease, Melanoma - Metastatic. Zelboraf may also be used for purposes not listed in this medication guide. |
Prescribed for Melanoma - Metastatic, Melanoma, Malignant Pleural Mesothelioma, Colorectal Cancer, Renal Cell Carcinoma. Yervoy may also be used for purposes not listed in this medication guide. |
Prescribed for Melanoma - Metastatic, Non-Small Cell Lung Cancer, Thyroid Cancer. Mekinist may also be used for purposes not listed in this medication guide. |
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Prescription only |
Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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Common side effects include: squamous cell carcinoma, keratoacanthoma, skin photosensitivity, erythema of skin. See the full Zelboraf side effects document. |
See the full Yervoy side effects document. |
Common side effects include: acneiform eruption, cardiomyopathy, decreased left ventricular ejection fraction, dermatitis, palmar-plantar erythrodysesthesia, skin rash, erythema of skin. See the full Mekinist side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all Zelboraf prices |
View all Yervoy prices |
View all Mekinist prices |
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Generic Availability |
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No |
No |
No |
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Dosage Form(s) Available |
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Brand Names |
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N/A |
N/A |
N/A |
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Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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120 hours |
352.8 hours |
115.2 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
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FDA Alerts |
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N/A |
N/A |
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Drug Interactions |
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A total of 536 drugs are known to interact with Zelboraf:
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A total of 136 drugs are known to interact with Yervoy:
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A total of 15 drugs are known to interact with Mekinist:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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August 17, 2011 |
March 25, 2011 |
May 29, 2013 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.