Simeprevir Alternatives Compared
Simeprevir | Epclusa | Mavyret |
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Simeprevir | Epclusa (sofosbuvir / velpatasvir) | Mavyret (glecaprevir / pibrentasvir) |
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Prescription only
Prescribed for Hepatitis C. simeprevir may also be used for purposes not listed in this medication guide. |
Prescription only
Epclusa is a combination tablet containing velpatasvir and sofosbuvir. It may be used to treat all six genotypes of the hepatitis C virus in adults and children over the age of three. It is usually... View more |
Prescription only
Mavyret is an antiviral combination agent that is approved to treat all six genotypes (1-6) of hepatitis C virus (HCV) in adults and children aged 12 years of age and older. It is one of the most... View more |
Related suggestions |
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More about Simeprevir | More about Epclusa (sofosbuvir / velpatasvir) | More about Mavyret (glecaprevir / pibrentasvir) | ||||||||||||||||
Ratings & Reviews | ||||||||||||||||||
Simeprevir has an average rating of 9.7 out of 10 from a total of 4 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Epclusa has an average rating of 7.7 out of 10 from a total of 392 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 12% reported a negative effect. |
Mavyret has an average rating of 8.4 out of 10 from a total of 421 ratings on Drugs.com. 79% of reviewers reported a positive effect, while 8% reported a negative effect. |
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Drug Class | ||||||||||||||||||
Side Effects | ||||||||||||||||||
See also: simeprevir side effects in more detail. |
See also: Epclusa side effects in more detail. |
See also: Mavyret side effects in more detail. |
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Generic Availability | ||||||||||||||||||
N/A |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Epclusa prices |
View all Mavyret prices |
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Dosage Forms Available | ||||||||||||||||||
N/A |
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Brand Names | ||||||||||||||||||
N/A |
N/A |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
41 hours |
27 hours |
13 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||
A total of 193 drugs are known to interact with simeprevir:
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A total of 188 drugs are known to interact with Epclusa:
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A total of 190 drugs are known to interact with Mavyret:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||
No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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First Approval Date | ||||||||||||||||||
N/A |
June 28, 2016 |
August 03, 2017 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||
Patient resources | ||||||||||||||||||
Professional Resources | ||||||||||||||||||
N/A |
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Related Treatment Guide | ||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.