Simeprevir Drug Interactions
A total of 137 drugs (443 brand and generic names) are known to interact with simeprevir.
- 75 major drug interactions (262 brand and generic names)
- 62 moderate drug interactions (181 brand and generic names)
Check for interactions with simeprevir
Common medications checked in combination with simeprevir
- Adderall XR (amphetamine / dextroamphetamine)
- Aloprim (allopurinol)
- Augmentin (amoxicillin / clavulanate)
- Bactrim (sulfamethoxazole / trimethoprim)
- Celestone (betamethasone)
- Chlorpheniramine (Allergy) (chlorpheniramine)
- Cymbalta (duloxetine)
- Delzicol (mesalamine)
- Dextrose (glucose)
- Fentanyl Transdermal System (fentanyl)
- Geodon (ziprasidone)
- Hydro Par (hydrochlorothiazide)
- Isentress (raltegravir)
- Paracetamol (acetaminophen)
- Sovaldi (sofosbuvir)
- Soya Lecithin (lecithin)
- Spiriva (tiotropium)
- Truvada (emtricitabine / tenofovir)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
simeprevir alcohol/food Interactions
There is 1 alcohol/food interaction with simeprevir
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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